Results 91 to 100 of about 63,694 (309)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
The Languages of Charles Reznikoff [PDF]
, 2011 This paper examines the representation of American everyday life and the language of the legal system in the work of Charles Reznikoff. It draws comparisons between Reznikoff's accounts of the lives of immigrants to America in his work, and Jacques ...
Davidson, Ian
core +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Performing weight change : a performative reading of reality-making through a relationship of meaning and doing : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in English at Massey University [PDF]
, 2009 Reading the reality-making processes that create bodies in weight change performances challenges us to understand the relationships between meanings and actions, or between discourses and materiality. This study uses a performative model to elaborate how
Caseley, Allyson June
core
, 2018 This paper explores the political impact of protest actions that explicitly make use of performance practices in their execution, and takes the activist work of Margaretta D’Arcy as the central object of analysis.
Duggan, Patrick
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Herding cats: observing live coding in the wild [PDF]
, 2014 After a momentous decade of live coding activities, this paper seeks to explore the practice with the aim of situating it in the history of contemporary arts and music.
Aaron S. +13 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Seeking out the spaces between: Using improvisation for collaborative composition and interactive technology [PDF]
, 2010 Copyright © 2010 ISASTThis article presents findings from experiments into piano performance live electronics undertaken by the author since early 2007.
Nicolls, S
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source