Results 31 to 40 of about 824,468 (289)

Automated Pixel-Wise Quantitative Myocardial Perfusion Mapping by Cardiovascular Magnetic Resonance to Detect Obstructive Coronary Artery Disease and Coronary Microvascular Dysfunction: Validation Against Invasive Coronary Physiology

open access: yesJACC Cardiovascular Imaging, 2019
Objectives To assess the performance of CMR myocardial perfusion mapping against invasive coronary physiology reference standards for detecting CAD (defined by fractional flow reserve (FFR)≤0.80), MVD (defined by index of microcirculatory resistance (IMR)
T. Kotecha   +15 more
semanticscholar   +1 more source

Gammagrafía de la perfusión cerebral

open access: yesOncología, 2022
Se comentan en este artículo aspectos importantes de la Gammagrafía de perfusión cerebral, y sus diversas aplicaciones clínicas en las enfermedades neurológicas. Se enfoca además la utilidad de la Tomografía por emisión de fotón único (SPECT) Cerebral y
Silvia Vázquez
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Cardiopulmonary bypass for total aortic arch replacement surgery: A review of three techniques

open access: yesFrontiers in Cardiovascular Medicine, 2023
One treatment for acute type A aortic dissection is to replace the ascending aorta and aortic arch with a graft during circulatory arrest of the lower body, but this is associated with high mortality and morbidity.
Ying Cui   +5 more
doaj   +1 more source

Observations on the ex situ perfusion of livers for transplantation

open access: yesAmerican Journal of Transplantation, 2018
Normothermic ex situ liver perfusion might allow viability assessment of livers before transplantation. Perfusion characteristics were studied in 47 liver perfusions, of which 22 resulted in transplants.
C. Watson   +11 more
semanticscholar   +1 more source

Perfusión tisular: consideraciones básicas y clínicas fundamentos de medicina traslacional [PDF]

open access: yes, 2014
La perfusión tisular es un concepto fundamental en fisiología y medicina clínica. Conceptualmente complejo por la inclusión de múltiples procesos que integran fisiología cardiovascular en términos macrohemodinámicos, fisiología del transporte de gases ...
Aldana Díaz, José Luis
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Trasplante cardiaco en cardiopatías congénitas. Peculiaridades técnicas

open access: yesCirugía Cardiovascular, 2019
Resumen: El trasplante en cardiopatías congénitas supone alrededor de un 10% del total. Aunque básicamente se trata de un procedimiento similar al de un trasplante convencional en un adulto, incluye peculiaridades técnicas propias de la cirugía infantil.
Juan-Miguel Gil-Jaurena   +8 more
doaj   +1 more source

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