Results 91 to 100 of about 907,151 (342)

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Simulated cardiopulmonary bypass: a high fidelity model for developing and accessing clinical perfusion skills

Advances in Simulation
Background Traditionally, novice perfusionists learn and practice clinical skills, during live surgical procedures. The profession’s accrediting body is directing schools to implement simulated cardiopulmonary bypass (CPB) into the curriculum ...
Bruce E. Searles, Jeffrey B. Riley, Edward M. Darling, Jason R. Wiles   +3 more
doaj   +1 more source

Computer-assisted ex vivo, normothermic small bowel perfusion [PDF]

, 2000
Background: In the present study, a technique for computer-assisted, normothermic, oxygenated, ex vivo, recirculating small bowel perfusion was established as a tool to investigate organ pretreatment protocols and ischemia/reperfusion phenomena.
Eder, M., Hammer, C., Krapp, J., Land, W., Schildberg, Friedrich Wilhelm, Stangl, M. J., Theodorou, D.   +6 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Antisecretory Action of the Extract of the Aerial Parts of Eremomastax speciosa (Acanthaceae) Occurs through Antihistaminic and Anticholinergic Pathways

Advances in Pharmacological Sciences, 2014
Objective. The objective of this study was to find out the possible antiulcer mechanism of action of Eremomastax speciosa. Method. Carbachol- and histamine-induced hypersecretion, associated with the pylorus ligation technique, were used in rats. Gastric
Amang André Perfusion, Paul V. Tan, Nkwengoua Ernestine, Nyasse Barthélemy   +3 more
doaj   +1 more source

Regional association of pCASL-MRI with FDG-PET and PiB-PET in people at risk for autosomal dominant Alzheimer's disease. [PDF]

, 2018
Autosomal dominant Alzheimer's disease (ADAD) is a small subset of Alzheimer's disease that is genetically determined with 100% penetrance. It provides a valuable window into studying the course of pathologic processes that leads to dementia.
Coppola, Giovanni, Huang, Sung-Cheng, Jann, Kay, Liu, Collin Y, Mack, Wendy J, Ringman, John M, Wang, Danny JJ, Wong, Koon-Pong, Yan, Lirong   +8 more
core   +3 more sources

Serum vascular endothelial growth factor affects tissue fluid accumulation and is associated with deteriorating tissue perfusion and oxygenation in severe sepsis: a prospective observational study [PDF]

, 2023
Chin‐Kuo Lin, Ying‐Huang Tsai, Kuo‐Chin Kao, Chieh‐Mo Lin, Shao-Kui Zhou, Meng-Chin Ho, Shu‐Yi Huang, Yu‐Hung Fang, Che‐Chia Chang, Wei‐Chun Lee, Yueh‐Lin Lee, Min‐Chi Chen, Meng‐Jer Hsieh, Yu‐Ching Lin, Ming‐Szu Hung, Wen-Chun Kuo, Bor‐Shyh Lin   +16 more
openalex   +1 more source

Harnessing Non‐Covalent Protein–Protein Interaction Domains for Production of Biocatalytic Materials Systems

Advanced Functional Materials, EarlyView.
Non‐covalent protein–protein interactions mediated by SH3, PDZ, or GBD domains enable the self‐assembly of stable and biocatalytically active hydrogel materials. These soft materials can be processed into monodisperse foams that, once dried, exhibit enhanced mechanical stability and activity and are easily integrated into microstructured flow ...
Julian S. Hertel, Maria Alessandra Martini, Marius Stoeckle, Annika J. Weber, Kersten S. Rabe, Christof M. Niemeyer   +5 more
wiley   +1 more source

Ventilation/perfusion SPECT/CT findings in different lung lesions associated with COVID-19: a case series [PDF]

, 2020
Nina Cobes, Mohamed Guernou, David Lussato, Mathieu Queneau, Bernard Songy, G. Bonardel, Jean-François Grellier   +6 more
openalex   +1 more source

Metal‐Organic Frameworks Facilitating Complexation for Long‐Cycle Zinc‐Bromine Flow Batteries

Advanced Functional Materials, EarlyView.
The organic ligands (imidazole and benzimidazole) from the decomposed zinc ZIF‐62 is proposed to further improve the Br2 complexing ability of the mature complexing agent (i.e., N‐methyl‐N‐ethyl pyrrolidinium bromide (MEP) ionic liquid). The synergistic effect between Im/BIm of the decomposed ZIF‐62 toward bromine species and MEP toward bromine species,
Huaiyang Zheng, Junwei Ding, Jiaqi Huang, Junrui Wang, Haitao Zhang, Congwen Qin, Junping Zhang, Yingjun Cai, Xiaoyan Ji   +8 more
wiley   +1 more source