Results 91 to 100 of about 1,215,000 (384)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

The feasibility of centralized application services for perfusion education programs

open access: yesThe Journal of ExtraCorporeal Technology
The perfusion profession has recently experienced significant advancements in education and practice. Despite competition from other healthcare professions, the demand for perfusionists continues to grow.
Johnson Blaine
doaj   +1 more source

Characterizing steady states of genome-scale metabolic networks in continuous cell cultures

open access: yes, 2017
We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct accumulation.
Fernandez-de-Cossio-Diaz, Jorge   +2 more
core   +3 more sources

Experimental studies on coronary perfusion with pump-oxygenator [PDF]

open access: yes, 1959
1. Methods of retrograde coronary perfusion and direct coronary artery perfusion in combination with a bubble oxygenator were investigated in dogs. 2.
Hayashi, Naomi
core   +1 more source

Normothermic Perfusion in the Assessment and Preservation of Declined Livers Before Transplantation: Hyperoxia and Vasoplegia—Important Lessons From the First 12 Cases

open access: yesTransplantation, 2017
Background A program of normothermic ex situ liver perfusion (NESLiP) was developed to facilitate better assessment and use of marginal livers, while minimizing cold ischemia. Methods Declined marginal livers and those offered for research were evaluated.
C. Watson   +8 more
semanticscholar   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou   +4 more
wiley   +1 more source

The feasibility of a national matching service for perfusion education program applicants

open access: yesThe Journal of ExtraCorporeal Technology
The perfusion profession is experiencing rapid advancement, creating an array of new opportunities for professional growth and educational expansion.
Johnson Blaine
doaj   +1 more source

Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]

open access: yes, 2011
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Barrie Condon   +9 more
core   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

open access: yesAdvanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram   +5 more
wiley   +1 more source

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