Results 101 to 110 of about 497,841 (322)

Biofunctionalization of ADA‐GEL Hydrogels Based on the Degree of Cross‐Linking and Polymer Concentration Improves Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biocompatibility of alginate dialdehyde (ADA) and gelatin (GEL) hydrogels cross‐linked with human transglutaminase (hTG) is demonstrated in vivo with a high degree of stability and angiogenic potential. The additional enzymatic cross‐linker hTG and the increased concentration improve stability and angiogenic potential. The X‐ray microscopy (XRM) is
Stefanie Heltmann‐Meyer   +12 more
wiley   +1 more source

Isolated lung perfusion

open access: yesFrontiers in Bioscience, 2012
Isolated lung perfusion (ILP) has been historically used as a method to study basic lung physiologic concepts using animal models. More recently, ILP has been applied in lung transplantation and thoracic oncology. In lung transplantation, ILP has been used to assess physiological integrity of donor lungs after the organ is removed from the donor.
Shaf Keshavjee, Marcelo Cypel
openaire   +3 more sources

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

open access: yesAdvanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll   +16 more
wiley   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

open access: yesAdvanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu   +4 more
wiley   +1 more source

Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications

open access: yesAdvanced Materials, EarlyView.
A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung   +10 more
wiley   +1 more source

Unmasking culprits: novel analysis identifies complement factors as potential therapeutic targets to mitigate inflammation during children's heart surgery

open access: yesEuropean Journal of Medical Research
Background Cardiopulmonary bypass (CPB) causes systemic inflammation during pediatric cardiac surgery, which can contribute to post-operative organ dysfunction and prolonged recovery. This study aims to identify key inflammatory mediators related to this
Joel Bierer   +6 more
doaj   +1 more source

Optical Coherence Tomography Angiography in Glaucoma

open access: yesTürk Oftalmoloji Dergisi, 2018
Optical coherence tomography angiography (OCTA) comprises different OCT-based technologies developed for non-invasive assessment and measurement of optic nerve head and retinal perfusion. Currently the most clinically established approach is based on the
Gábor Holló
doaj   +1 more source

Normative Cerebral Perfusion Across the Lifespan [PDF]

open access: yesarXiv
Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization of its lifespan dynamics has been limited by small sample sizes and methodological inconsistencies. In this study,
arxiv  

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