Results 101 to 110 of about 848,845 (338)
Risk-Assessment of Esophageal Surgery: Diagnosis and Treatment of Celiac Trunk Stenosis
Anastomotic leakage of the gastric conduit following surgical treatment of esophageal cancer is a life-threatening complication. An important risk factor associated with anastomotic leakage is calcification of the supplying arteries of the gastric ...
Rosa G.M. Lammerts+3 more
doaj +1 more source
Background and Objectives: The cushioning effect of large, healthy arteries reduces pulsatile afterload to the heart, reduces pulsatility in the microvasculature of target organs, and promotes coronary/cerebral perfusion [1].
Florian Stefanov+5 more
doaj +1 more source
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino+9 more
wiley +1 more source
Sensing a Sensor: Identifying the Mechanosensory Function of Primary Cilia
Over the past decade, primary cilia have emerged as the premier means by which cells sense and transduce mechanical stimuli. Primary cilia are sensory organelles that have been shown to be vitally involved in the mechanosensation of urine in the renal ...
Rahul M. Prasad+2 more
doaj +1 more source
Integration of Electronic Perfusion Data for Perfusion Registries
Although the potential for the utilization of electronic perfusion data (EPD) from proprietary software to facilitate the understanding and improvement of cardiopulmonary bypass (CPB) has been recognized, the generalizability of previous reports of EPD integration are limited by superceded software or lack of sufficient detail for reproducibility.
Richard F, Newland+2 more
openaire +2 more sources
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Introduction: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure.
Butt Salman Pervaiz+4 more
doaj +1 more source
RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors. [PDF]
BackgroundThe tumor-specific microregional effects of the anticancer agent RRx-001, a novel epigenetic-based radio/chemosensitizer with nitrogen oxide-donating properties in phase II clinical trials, were investigated with whole tissue section ...
Cabrales, Pedro+3 more
core +2 more sources
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan+13 more
wiley +1 more source
Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia+8 more
core +2 more sources