Results 101 to 110 of about 848,845 (338)

Risk-Assessment of Esophageal Surgery: Diagnosis and Treatment of Celiac Trunk Stenosis

open access: yesThe Thoracic & Cardiovascular Surgeon Reports, 2018
Anastomotic leakage of the gastric conduit following surgical treatment of esophageal cancer is a life-threatening complication. An important risk factor associated with anastomotic leakage is calcification of the supplying arteries of the gastric ...
Rosa G.M. Lammerts   +3 more
doaj   +1 more source

P.68 WaveGraft–A Novel Endovascular Device Concept for Restoring the Natural Arterial Cushioning Effect

open access: yesArtery Research, 2020
Background and Objectives: The cushioning effect of large, healthy arteries reduces pulsatile afterload to the heart, reduces pulsatility in the microvasculature of target organs, and promotes coronary/cerebral perfusion [1].
Florian Stefanov   +5 more
doaj   +1 more source

Pericyte‐Assisted Vascular Lumen Organization in a Novel Dynamic Human Blood‐Brain Barrier‐on‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Organ‐on‐Chip (OoC) technology enables the precise modeling of the blood‐brain barrier (BBB). This study presents a microfluidic device that mimics brain microvessels, integrating co‐culture with pericytes and astrocytes under pulsatile flow. Results show that perivascular cells modulate endothelial morphology, promoting lumen formation and barrier ...
Vita Guarino   +9 more
wiley   +1 more source

Sensing a Sensor: Identifying the Mechanosensory Function of Primary Cilia

open access: yesBiosensors, 2014
Over the past decade, primary cilia have emerged as the premier means by which cells sense and transduce mechanical stimuli. Primary cilia are sensory organelles that have been shown to be vitally involved in the mechanosensation of urine in the renal ...
Rahul M. Prasad   +2 more
doaj   +1 more source

Integration of Electronic Perfusion Data for Perfusion Registries

open access: yesThe Journal of ExtraCorporeal Technology, 2018
Although the potential for the utilization of electronic perfusion data (EPD) from proprietary software to facilitate the understanding and improvement of cardiopulmonary bypass (CPB) has been recognized, the generalizability of previous reports of EPD integration are limited by superceded software or lack of sufficient detail for reproducibility.
Richard F, Newland   +2 more
openaire   +2 more sources

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Improving ECMO therapy: Monitoring oxygenator functionality and identifying key indicators, factors, and considerations for changeout

open access: yesThe Journal of ExtraCorporeal Technology
Introduction: The optimal timing for extracorporeal membrane oxygenation (ECMO) circuit change-out is crucial for the successful management of patients with severe cardiopulmonary failure.
Butt Salman Pervaiz   +4 more
doaj   +1 more source

RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors. [PDF]

open access: yes, 2016
BackgroundThe tumor-specific microregional effects of the anticancer agent RRx-001, a novel epigenetic-based radio/chemosensitizer with nitrogen oxide-donating properties in phase II clinical trials, were investigated with whole tissue section ...
Cabrales, Pedro   +3 more
core   +2 more sources

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan   +13 more
wiley   +1 more source

Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism [PDF]

open access: yes, 2015
Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, while the cerebral metabolic rate for oxygen (CMRO2) is preserved.
Benjamin Garcia   +8 more
core   +2 more sources

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