Results 121 to 130 of about 592,593 (299)

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

Advanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega, Kirthen Shanmuganathan, Laura Poole‐Warren, Susann Beier, Ulises Aregueta Robles   +4 more
wiley   +1 more source

The effect of albumin priming solution on platelet activation during experimental long-term perfusion

, 1998
The objective of this study was to evaluate the effect of albumin priming on platelet consumption and activation during long-term perfusion. Two identical in vitro extracorporeal membrane oxygenation circuits were used; one was primed with Ringer's ...
Friberg, Lars-Göran,, Adrian, Katrin,, Mellgren, Karin,, Skogby, Maria,, Mellgren, G, Wadenvik, Hans,   +5 more
core  

Diferencia de la presión arterial media antes y durante un bypass cardiopulmonar: ¿cuál debe ser la presión de perfusión media ideal?

Cirugía y Cirujanos
Objetivo: La diferencia de la presión arterial media (PAM) antes del bypass cardiopulmonar y la presión de perfusión media (PPM) durante el bypass cardiopulmonar se considera un factor predictivo importante de insuficiencia renal aguda (IRA).
Bişar Amaç, Murat Ersoy, Murat Z. Bağiş, Mahmut Padak   +3 more
doaj   +1 more source

Normothermic Perfusion is Superior to Cold Perfusion in Porcine Ex Situ Lung Perfusion

Transplantation Proceedings
Cold ex situ lung perfusion (ESLP) has demonstrated improved preservation in small animal ESLP compared to normothermic ESLP and cold static preservation. We hypothesized that cold negative pressure ventilation (NPV)-ESLP would improve graft function in a porcine transplantation model.Four perfusate temperatures were examined with 12 hours NPV-ESLP in ...
Keir Forgie, Nicholas Fialka, Abeline Watkins, Katie Du, Sayed Himmat, Sanaz Hatami, Mubashir Khan, Xiuhua Wang, Ryan Edgar, Katie-Marie Buswell-Zuk, Darren H. Freed, Jayan Nagendran   +11 more
openaire   +2 more sources

Dual Acidic pH‐Responsive Post‐Crosslinked E‐Spun Nanofibrous Scaffolds Exhibiting Enhanced Disassembly and Release for Localized Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Dual acidic pH‐responsive degradable e‐spun nanofibrous mats crosslinked with acid‐labile imine and boronic ester linkages that exhibit rapid degradation and enhanced release of encapsulated anticancer drugs through their acid‐catalyzed hydrolysis and their doxorubicin‐loaded mats having desired antitumoral activity and hemocompatibility, as promising ...
Sofia Nieves Casillas‐Popova, Arianna Cirillo, Cameron D. Skinner, Dajana Vuckovic, Jung Kwon Oh   +4 more
wiley   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Is it possible to further improve the function of pulmonary grafts by extending the duration of lung reconditioning using ex vivo lung perfusion?

, 2013
BACKGROUND: The method of ex vivo lung perfusion (EVLP) has been suggested as a reliable means of differentiating between "good" and "poor" pulmonary grafts in marginal donors as, when grafts identified as good by this method are transplanted, the ...
Pierre, Leif,, Lindstedt Ingemansson, Sandra,, Hlebowicz, Joanna,, Lund University., Ingemansson, Richard,   +4 more
core   +1 more source

A narrative review on miniaturized extracorporeal technology and circuits: a revolutionary approach to cardiac surgery

The Cardiothoracic Surgeon
Background The development of the cardiopulmonary bypass machine for extracorporeal circulation by Dr. John Gibbon marked a significant milestone in the advancement of medical technology.
Trasha Shetty, Anshuman Darbari, P. Sainath   +2 more
doaj   +1 more source

Determination of insensible water loss and sodium accumulation behavior from the Medtronic Nautilus Extracorporeal Membrane Oxygenation (ECMO) oxygenator: An in vitro study

The Journal of ExtraCorporeal Technology
Introduction: Fluid and electrolyte balance is closely managed in extracorporeal membrane oxygenation (ECMO) patients. Neglecting oxygenator-related insensible fluid losses can distort fluid balance and electrolyte levels.
Striker Carrie Whittaker, Kong Gabriel
doaj   +1 more source

Standardized Effect Measures Informing Next‐Generation Strategies for Mechanical Stimulation in Cartilage Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen, Tony B. Huang, Catherine E. Davey, Elias Salzer, Gerjo J. V. M. Van Osch, Sandra J. Shefelbine, Marcus G. Pandy, Kathryn S. Stok   +7 more
wiley   +1 more source