Results 141 to 150 of about 592,593 (299)

Thermally Modulated Metasurface Sensor for Dynamic and Time‐Resolved Isolation of Extracellular Vesicles

Advanced Materials, EarlyView.
A thermally adaptive plasmonic metasurface, functionalized with poly(N‐isopropylacrylamide) (PNIPAM) and anti‐CD63 antibodies, enables precise, on‐demand capture and release of extracellular vesicles (EVs). Delivering high recovery, improved purity, and intact vesicle structure, the platform offers a versatile, label‐free solution for real‐time EV ...
Beyza Nur Kucuk, Eylul Gulsen Yilmaz, Yusuf Aslan, Emre Ece, Özgecan Erdem, Murat Alp Gungen, Bengi Özgün Öztürk, Fatih Inci   +7 more
wiley   +1 more source

The relationship between parameters measured using intravoxel incoherent motion and dynamic contrast-enhanced MRI in patients with breast cancer undergoing neoadjuvant chemotherapy: a longitudinal cohort study

Frontiers in Oncology
PurposeThe primary aim of this study was to explore whether intravoxel incoherent motion (IVIM) can offer a contrast-agent-free alternative to dynamic contrast-enhanced (DCE)-MRI for measuring breast tumor perfusion.
Zyad M. Almutlaq, Zyad M. Almutlaq, Sarah E. Bacon, Daniel J. Wilson, Nisha Sharma, Tatendashe Dondo, David L. Buckley   +6 more
doaj   +1 more source

Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release

Advanced Materials, EarlyView.
A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni, Nitzan Letko Khait, Adam Forman, Edward A. Armstrong, Karim Fouad, Molly S. Shoichet   +5 more
wiley   +1 more source

3D bioprinting for the production of a perfusable vascularized model of a cancer niche

Frontiers in Bioengineering and Biotechnology
The ever-growing need for improved in vitro models of human tissues to study both healthy and diseased states is advancing the use of techniques such as 3D Bioprinting.
Federico Maggiotto, Federico Maggiotto, Lorenzo Bova, Lorenzo Bova, Lorenzo Bova, Sara Micheli, Sara Micheli, Camilla Pozzer, Pina Fusco, Pina Fusco, Paolo Sgarbossa, Fabrizio Billi, Elisa Cimetta, Elisa Cimetta   +13 more
doaj   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Estimation of reference curves for brain atrophy and analysis of robustness to machine effects

Scientific Reports
Neurodegenerative diseases like Alzheimer’s are difficult to diagnose due to brain complexity and imaging variability. However, volumetric analysis tools, using reference curves, help detect abnormal brain atrophy and support diagnosis and monitoring ...
Elodie Piot, Félix Renard, Arnaud Attyé, Alexandre Krainik, for the Alzheimer’s Disease Neuroimaging Initiative, For the Frontotemporal Lobar Degeneration Neuroimaging Initiative   +5 more
doaj   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem

Scientific Reports
Activation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis.
Joel David Bierer, Roger Stanzel, Mark Henderson, Tony El-Rabahi, John Sapp, Pantelis Andreou, Jean S. Marshall, David Conrad, David Horne   +8 more
doaj   +1 more source

Changes in perfusion and permeability in glioblastoma model induced by the anti-angiogenic agents cediranib and thalidomide

Acta Oncologica
Background and purpose: The poor delivery of drugs to infiltrating tumor cells contributes to therapeutic failure in glioblastoma. During the early phase of an anti-angiogenic treatment, a remodeling of the tumor vasculature could occur, leading to a ...
Jérôme Conq, Nicolas Joudiou, Véronique Préat, Bernard Gallez   +3 more
doaj   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source