Results 141 to 150 of about 907,151 (342)

The relationship between parameters measured using intravoxel incoherent motion and dynamic contrast-enhanced MRI in patients with breast cancer undergoing neoadjuvant chemotherapy: a longitudinal cohort study

open access: yesFrontiers in Oncology
PurposeThe primary aim of this study was to explore whether intravoxel incoherent motion (IVIM) can offer a contrast-agent-free alternative to dynamic contrast-enhanced (DCE)-MRI for measuring breast tumor perfusion.
Zyad M. Almutlaq   +6 more
doaj   +1 more source

Comparison of multi-delay FAIR and pCASL labeling approaches for renal perfusion quantification at 3T MRI [PDF]

open access: hybrid, 2019
Anita A. Harteveld   +5 more
openalex   +1 more source

Visible Light Induced DLP‐Printed Oxygen‐Releasing TPMS Scaffolds Mitigate Early Hypoxia in Bone Defects

open access: yesAdvanced Healthcare Materials, EarlyView.
Visible light‐induced digital light processing 3D printed Primitive‐triply periodic minimal surface hydrogels embed CaO2–Si core–shell nanoparticles to deliver short‐term oxygen during the avascular window. The scaffolds maintain cytocompatibility, elevate osteopontin in vitro, and enhance calvarial defect repair in vivo without toxicity.
Anastasia B. Timoshenko   +11 more
wiley   +1 more source

3D bioprinting for the production of a perfusable vascularized model of a cancer niche

open access: yesFrontiers in Bioengineering and Biotechnology
The ever-growing need for improved in vitro models of human tissues to study both healthy and diseased states is advancing the use of techniques such as 3D Bioprinting.
Federico Maggiotto   +13 more
doaj   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim   +5 more
wiley   +1 more source

Unmasking culprits: novel analysis identifies complement factors as potential therapeutic targets to mitigate inflammation during children's heart surgery

open access: yesEuropean Journal of Medical Research
Background Cardiopulmonary bypass (CPB) causes systemic inflammation during pediatric cardiac surgery, which can contribute to post-operative organ dysfunction and prolonged recovery. This study aims to identify key inflammatory mediators related to this
Joel Bierer   +6 more
doaj   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger   +7 more
wiley   +1 more source

Complement activation by the artificial surface of cardiopulmonary bypass is a persistent clinical problem

open access: yesScientific Reports
Activation of the alternative complement pathway by artificial extracorporeal surfaces is relevant to several clinical applications such as cardiac surgery with cardiopulmonary bypass (CPB), thoracic organ transplantation and hemodialysis.
Joel David Bierer   +8 more
doaj   +1 more source

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