Results 211 to 220 of about 645,807 (300)
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Junwen Wang +8 more
wiley +1 more source
Effects of End-ischemic Hypothermic Oxygenated Perfusion on 1-y Graft Function in Kidney Transplantation: A Real-world, Single-center Analysis From the United States. [PDF]
Steggerda JA +17 more
europepmc +1 more source
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen +11 more
wiley +1 more source
Effect of intravenously administered norepinephrine on early postoperative tissue perfusion of radial free forearm flaps in the head and neck region - retrospective analysis in the context of continuous flap monitoring. [PDF]
Ooms M +7 more
europepmc +1 more source
Pressure overload suppresses cardiomyocyte ZER1, weakening CRL2Zer1‐mediated DVL2 degradation and allowing DVL2 accumulation. Elevated DVL2 activates CaMKII‐HDAC4‐MEF2C signaling, drives fetal gene reactivation, and promotes pathological remodeling.
Mingchao Jiang +27 more
wiley +1 more source
Stress CT myocardial perfusion imaging after arterial switch operation for transposition of the great arteries. [PDF]
Gkizas C +9 more
europepmc +1 more source
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li +8 more
wiley +1 more source
A vascular calcification model enabled by an <i>ex vivo</i> vascular calcification perfusion system. [PDF]
Li J +6 more
europepmc +1 more source
Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen +11 more
wiley +1 more source

