Results 231 to 240 of about 832,905 (305)

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Balloon Fracture Fenestration after Frozen Elephant Trunk Deployment to Eliminate Retrograde False-Lumen Perfusion in a Type B Dissection-Complicated Arch Aneurysm. [PDF]

Surg Case Rep
Takagi D, Yamaura G, Kiryu K, Arai T, Igarashi I, Yamazaki Y, Igarashi W, Nakajima H.   +7 more
europepmc   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Enhancing Hand Vascular Assessment: The Role of Hyperspectral Imaging in Perfusion Monitoring. [PDF]

J Hand Surg Glob Online
Ganesan O, Trost J, Pike MD, Sampson RD, Holzmer S, Talbot S, Sampson CE.   +6 more
europepmc   +1 more source

Perfusion

Res Medica, 2013
openaire   +2 more sources

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Isolation of primary hepatocytes and non-parenchymal cells from mouse fatty liver. [PDF]

MethodsX
Zhuo X, Wang K, Shi Y, Wang X, Zhan H, Yu J, Li J, Tudimaimaiti A, Wang X.   +8 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Myocardial Viability and Ischaemia in Chronic Total Occlusion. [PDF]

Medicina (Kaunas)
Mehmood Z, Suresh P, Li R, Assadi H, Kasmai B, Thampi K, Maart C, Gilbert T, Eccleshall S, Sawh C, Nair S, van der Geest RJ, Vassiliou VS, Ryding A, Matthews G, Garg P.   +15 more
europepmc   +1 more source