Results 221 to 230 of about 592,593 (299)

Quantitative evaluation of free anterolateral thigh flap perfusion using indocyanine green angiography: A retrospective analysis of 13 consecutive cases. [PDF]

Medicine (Baltimore)
Dong S, Hou X, Cao Y, Wang S, Wang G, Liu Y, Zhang Y, Wu C, Ju J, Wang K.   +9 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Aspirin therapy after heart transplantation is associated with higher myocardial perfusion reserve assessed by cardiovascular magnetic resonance imaging. [PDF]

JHLT Open
Jablonowski R, Löfman IH, Andersson HB, Gjesdal G, Fogarasi C, Kellman P, Melin M, Engblom H, Arheden H, Carlsson M, Nickander J, Braun OÖ.   +11 more
europepmc   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Protocol for isolation of lipid-laden hepatocytes from high-fat diet-fed and metabolically challenged mice. [PDF]

STAR Protoc
Ponnusamy T, Natarajaseenivasan K, Shanmughapriya S.   +2 more
europepmc   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Optimized cellular perfusate increases lung viability ex vivo and extends the duration of ex vivo lung perfusion. [PDF]

J Heart Lung Transplant
Arnold CJ, Nakata K, Hassan A, Alderete I, Aykun N, Abraham N, Carney J, Xiang Y, Kamaleswaran R, Jiang H, Hughes BA, Barbas AS, Hartwig MG.   +12 more
europepmc   +1 more source

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

Advanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim, Huajie Wang, Gao Qianqian, Abdul Waris, Jufang He   +4 more
wiley   +1 more source

4th workshop purification therapies, from research to clinics "the end of the beginning": executive summary. [PDF]

Transpl Int
Atti M, Remuzzi G, Feltrin G, Oniscu GC, Porte RJ, Ranieri M, Rinaldi M, Vincent JL.   +7 more
europepmc   +1 more source