Results 231 to 240 of about 825,159 (286)

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

The role of multimodal ultrasound in assessing renal microcirculatory perfusion in cases of acute kidney injury. [PDF]

BMC Nephrol
Qi M, Shen H, Li Y, Zhang J, Li J.
europepmc   +1 more source

Perfusion

Res Medica, 2013
openaire   +2 more sources

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Diagnostically competitive performance of a physiology-informed generative multi-task network for contrast-free CT perfusion. [PDF]

Front Hum Neurosci
Khan W, Rees J, See KB, Kato S, Huang Z, Lazarte A, Douglas K, Lou X, Peng TJ, Rajderkar D, Sanelli P, Singh A, Tuna I, Wilson CA, Fang R.   +14 more
europepmc   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Differentiating ischemic from healthy myocardium using cardiovascular magnetic resonance dipyridamole rest and stress T1 mapping. [PDF]

Sci Rep
Chang YT, Chien CY, Huang WM, Hung CL, Zhang Q, Gonzales RA, Burrage MK, Piechnik SK, Ferreira VM, Yun CH.   +9 more
europepmc   +1 more source

Correlation Between Small Dense Low-Density Lipoprotein and Tissue Perfusion in Diabetic Foot. [PDF]

J Korean Med Sci
Lee KI, Choi YW, Han SK, Jeong SH, Dhong ES.   +4 more
europepmc   +1 more source

Unilateral pulmonary oedema caused by eccentric mitral regurgitation-multimodality evidence of mechanism and reversal after transcatheter edge-to-edge repair: a case report. [PDF]

Eur Heart J Case Rep
Yoshida J, Uno G, Okuyama T, Ogawa T, Tokuda M.   +4 more
europepmc   +1 more source