Results 121 to 130 of about 4,249,101 (249)

Characterization of the glymphatic system and early-phase β-amyloid imaging in Alzheimer's disease: A simultaneous PET/MR study

Brain Research Bulletin
Early-phase Aβ imaging can detect cerebral perfusion deficits, while glymphatic dysfunction is a key event in neurodegenerative diseases, including Alzheimer's disease (AD). However, their relationship within the AD continuum remains unclear.
Yuying Jiao, Wei Han, Linhan Zhang, Mengjiao Wang, Zhehao Lyu, Yexin Su, Zeyu Wang, Lifan Wang, Jiafu Wang, Peng Xu, Yujie Hu, Yang Yang, Peng Fu   +12 more
doaj   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Phlethysmographic Continuous Detection of Variation of Systemic Blood Pressure during Spinal Anaesthesia in Caesarean Section: A Prospective Observational, Single-centre Study

NMO Journal
Introduction: Hypotension, a common side effect of spinal anaesthesia, is observed due to a negative influence on sympathetic tone. This study aimed to examine whether perfusion index (PI) and relative dicrotic notch height (Dicrpleth), two parameters ...
Sanjay Kumar, Sandeep Khuba, Rafat Shamim, Prabhakar Mishra, Aritra Banerjee, Sikha Khati, Nupur Gupta, Kanika Chaudhary   +7 more
doaj   +1 more source

Effects of different approaches of infraclavicular brachial plexus block on perfusion index and tissue perfusion

Annals of Medicine
Although both the lateral sagittal and costoclavicular approaches are applied at the cord level in the infraclavicular region, there is a major difference between the distributions of the two approaches. We aimed to investigate the effects of this different distribution on tissue perfusion and oxygenation.Sixty patients undergoing elective elbow ...
Çağdaş Baytar, Bengü Gülhan Köksal
openaire   +4 more sources

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Evaluation of perfusion index as a predictor of successful caudal block in pediatric patients: A prospective randomized study

Journal of Anaesthesiology Clinical Pharmacology
Background and Aims: Caudal block is among the most widely administered regional anesthesia in pediatric patients. The clinical signs and objective assessments are not fast and reliable enough to provide a good feedback.
Sumedha Vashishth, Nancy Nandal, Kiranpreet Kaur, Yogender S. Kadian, Sanjay Johar, Svareen Kaur, Mamta Bhardwaj, Vaishali Mahor   +7 more
doaj   +1 more source

Robustness of Under-sampled Optical Measurements of a Capillary Perfusion Index to Estimate Cerebral Blood Flow Heterogeneity

We implemented and tested an auto-covariance based method to calculate a perfusion index for two-photon imaging data of vascular networks to evaluate the heterogeneity of brain perfusion, an emerging indicator of ischemia.
Aarohi Deshpande, Alberto L. Vazquez
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Additional file 1: of Clinical classification of tissue perfusion based on the central venous oxygen saturation and the peripheral perfusion index

, 2016
Results: difference between the patients with peripheral perfusion index (PI) ≤0.6 and with PI >0.6 at 8 h (T8) after resuscitation.
Yun Long (1421299), Dawei Liu (156201), Huaiwu He (3578915), Xiaoting Wang (206653), Xiang Zhou (164107)   +4 more
core   +1 more source