Results 41 to 50 of about 4,249,101 (249)

Hemodialysis-induced renal perfusion decline: unraveling the pathophysiological mechanisms linking intradialytic circulatory stress to residual renal function loss

Frontiers in Pharmacology
BackgroundResidual renal function (RRF) plays a critical role in quality of life and survival in hemodialysis (HD) patients but characteristically declines after the initiation of HD.
Dayang Xie, Jiaming Tan, Qingtao Zhang, Qian Yu, Yiqin Wang, Yujin Wang, Li Gao, Liyuan Yan, Jianhui Zhou, Nan Li, Guangyan Cai   +10 more
doaj   +1 more source

Perfusion Collateral Index versus Hypoperfusion Intensity Ratio in Assessment of Collaterals in Patients with Acute Ischemic Stroke. [PDF]

, 2023
BACKGROUND AND PURPOSE: Perfusion-based collateral indices such as the perfusion collateral index and the hypoperfusion intensity ratio have shown promise in the assessment of collaterals in patients with acute ischemic stroke.
Polson, Jennifer, Liebeskind, David, Qiao, Joe, Colby, Geoffrey, Nour, May, Nael, Kambiz, Tsui, Brian, Salamon, Noriko, Chen, Iris, Tateshima, Satoshi, Duckwiler, Gary, ZHANG, HAOYUE, Bahr-Hosseini, Mersedeh, Jahan, Reza, Tavakkol, Elham, Saver, Jeffrey, Kihira, Shingo, Arnold, Corey, Villablanca, Juan   +18 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Comparative Validation of Blood Gas Analysis, Perfusion Index, and AKIN and RIFLE Scoring Systems in the Diagnosis of Acute Kidney Injury

Global Emergency and Critical Care
Objective: This study aimed to evaluate the potential role of the Peripheral Perfusion Index (PI) and arterial blood gas parameters as early indicators of acute kidney injury (AKI) and to compare their diagnostic utility with the Acute Kidney Injury ...
Kazım Ersin Altınsoy
doaj   +1 more source

Perfusion index versus non-invasive hemodynamic parameters during insertion of i-gel, classic laryngeal mask airway and endotracheal tube

Indian Journal of Anaesthesia, 2013
Background: Perfusion index (PI) is a non-invasive numerical value of peripheral perfusion obtained from a pulse oximeter. In this study, we evaluated the efficacy of PI for detecting haemodynamic stress responses to insertion of i-gel, laryngeal mask ...
Hosam M Atef, Salah Abd Fattah, Mohammed Emad Abd Gaffer, Ahamed Abd Al Rahman   +3 more
doaj   +1 more source

Possibilities of differentiation of solitary focal liver lesions by computed tomography perfusion [PDF]

Medicinski Glasnik, 2015
Aim To evaluate possibilities of computed tomography (CT) perfusion in differentiation of solitary focal liver lesions based on their characteristic vascularization through perfusion parameters analysis.
Irmina Sefić Pašić, Anes Pašić, Spomenka Kristić, Adnan Beganović, Aladin Čarovac, Amra Dzananovic, Lidija Lincender, Sandra Vegar Zubović   +7 more
doaj   +1 more source

Measurement of myocardial perfusion index.

, 2016
(A) Segment from representative mid-ventricular slice during first-pass perfusion imaging during peak dose dobutamine stress. Red region of interest defines the middle of the left ventricle (LV) for measuring the slope of blood, and the green circle ...
Craig A. Hamilton (844918), Sandra Soots (844920), Michael E. Hall (844915), Haroon Chughtai (844916), Jennifer H. Jordan (844919), W. Gregory Hundley (332555), Timothy M. Morgan (844917), Tina E. Brinkley (337907), R. Brandon Stacey (380950)   +8 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

In Patients With Hypertension, the Cortical Perfusion Index Measured by Contrast Enhanced Ultrasound Reveals a Sexual Dimorphism

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Arterial hypertension is characterized by microvasculature changes and reduced tissue perfusion. It is unknown whether a sexual dimorphism of renal microcirculation is present in patients with arterial hypertension.
Aikaterini Damianaki, Mariëlle Hendriks‐Balk, Wendy Brito, Erietta Polychronopoulou, Kenji Theiler, Menno Pruijm, Grégoire Wuerzner   +6 more
doaj   +1 more source