Results 61 to 70 of about 9,619 (252)

Changes in the Plethysmographic Perfusion Index During an End-Expiratory Occlusion Detect a Positive Passive Leg Raising Test*

, 2020
International audienceObjectives: The end-expiratory occlusion test for assessing preload responsiveness consists in interrupting mechanical ventilation for 15 seconds at end-expiration and measuring the cardiac index changes.
Nello De Vita, Monnet, Xavier, Gavelli, Francesco, Jean-Louis Teboul, Teboul, Jean-Louis, Beurton, Alexandra, Francesco Gavelli, Xavier Monnet, de Vita, Nello, Alexandra Beurton   +9 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

An observational study to correlate arterial lactate level and peripheral perfusion index in context of tissue perfusion in sepsis

, 2023
Background: In view of goal directed therapies, the predictive value of the course of peripheral perfusion parameters over time has not been studied. Moreover serial assessment of peripheral perfusion index (PI) can be more predictive for mortality when ...
Mahajan, Sanket K., Priyanka R. Singla, Singla, Priyanka R., Sanket K. Mahajan   +3 more
core   +2 more sources

Optimizing the timing of painless gastroscope insertion: integrating advanced monitoring tools to enhance safety and efficacy: a narrative review

Frontiers in Medicine
Painless gastroscopy demonstrates significant improvement in patient comfort and examination compliance, which might indicate that the procedure has become commonly used in clinical practice. However, the critical step of accurately determining insertion
Chunyan Li, Hongmei Zhou, Shuai Kang, Yipan Wu, Li Hu, Yun Xiong   +5 more
doaj   +1 more source

Effect of nerve growth factor dimeric mimetic GK-2 on microcirculation in skeletal muscle on the hind limb ischemia model in rats

Фармакокинетика и Фармакодинамика, 2021
The purpose of the study. In experiments on a hind limb ischemia model in rats, the effect of the TrkA-receptor agonist of the NGF 4th loop dimeric dipeptide mimetic compound GK-2 has been studied on microcirculation in ischemic skeletal muscle.Methods ...
I. B. Tsorin, A. O. Efimova, E. S. Pekeldina, M. B. Vititnova, S. A. Kryzhanovskii   +4 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Microcirculation Monitoring in Septic Shock: Focused Review

Medicina
Background and Objectives: Septic shock is marked by profound circulatory and cellular dysfunction, with mortality rates of 25–40% despite guideline-based resuscitation. Normalization of macrohemodynamic variables often fails to restore tissue perfusion,
Viktorija Serova, Mara Klibus, Zbignevs Marcinkevics, Uldis Rubins, Andris Grabovskis, Olegs Sabelnikovs   +5 more
doaj   +1 more source

Clinical and CMR characteristics in NICM patients with vs. without impaired myocardial perfusion reserve index.

, 2022
Clinical and CMR characteristics in NICM patients with vs. without impaired myocardial perfusion reserve index.
Jeremy A. Slivnick (14142030), Vien T. Truong (4675486), Karolina M. Zareba (14142033), Wojciech Mazur (4675495), Philip Binkley (8055227), Alexis Barnes (14142039), Ellen Liu (14142036)   +6 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source