Results 61 to 70 of about 4,249,101 (249)
FEBS Open Bio, EarlyView.During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa +4 more
wiley +1 more source
Microcirculation Monitoring in Septic Shock: Focused Review
MedicinaBackground and Objectives: Septic shock is marked by profound circulatory and cellular dysfunction, with mortality rates of 25–40% despite guideline-based resuscitation. Normalization of macrohemodynamic variables often fails to restore tissue perfusion,
Viktorija Serova +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Spatio-Temporal Modelling of Perfusion Cardiovascular MRI [PDF]
, 2010 Myocardial perfusion MRI provides valuable insight into how coronary artery and microvascular diseases affect myocardial tissue. Stenosis in a coronary vessel leads to reduced maximum blood flow (MBF), but collaterals may secure the blood supply of the ...
Schmid, Volker J.
core +1 more source
Using the Perfusion Index for Block Success in Pediatric Patients: A Retrospective Study
, 2023 Study objective: To investigate the efficacy of the perfusion index in assessing block success in pediatric patients undergoing elective supracondylar fracture repair surgery. Methods: It was a retrospective study in a tertiary-care center.
Sahin, Ayca Sultan +5 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Perfusion-weighted FREE map using a bSSFP sequence at 3T with a flip angle of 70°.
, 2022 A temporal perfusion-weighted MIP is showing the maximal amplitude of the entire heart cycle for each voxel (a) and the perfusion-weighted map (b) is presenting the maximum median amplitude within the parenchyma ROI.
Frank Wacker (281957) +9 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Three-dimensional cell culture and tissue engineering in a T-CUP (tissue culture under perfusion) [PDF]
, 2007 The aim of this study was to develop and validate a simple and compact bioreactor system for perfusion cell seeding and culture through 3-dimensional porous scaffolds.
Früh, Jennifer-Annika +5 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source