Results 321 to 330 of about 106,411 (380)

Brain pericytes derived from human pluripotent stem cells retain vascular and phagocytic functions under hypoxia. [PDF]

Stem Cells
Zhang M, Kim Y, Bosworth A, Tcw J, Nih LR, Kisler K, Sagare AP, Rust R.   +7 more
europepmc   +1 more source

Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro [PDF]

, 2015
Ashkan, Keyoumars, Butt, Arthur M., Fillmore, Helen L., Higgins, Samantha C., Pilkington, Geoffrey J.   +4 more
core   +1 more source

TREM2+ macrophages accumulate in childhood IgA nephropathy and soluble TREM2 represents a reliable non‐invasive biomarker

Experimental Physiology, EarlyView.
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu, Xuan Gang, Jingjing Wang, Guoping Huang, Qiuyu Li, Weizhong Gu, Haidong Fu, Jianhua Mao   +7 more
wiley   +1 more source

Detection of vasculogenic mimicry in equine ocular, oronasal, and genital squamous cell carcinoma. [PDF]

PLoS One
Schwarz S, Kummer S, Klang A, Walter I, Nell B, Brandt S.   +5 more
europepmc   +1 more source

Adipose tissue‐derived small extracellular vesicles and blood–brain barrier function in adults with overweight and obesity

Experimental Physiology, EarlyView.
Abstract Obesity is associated with adverse changes in brain structure and function, in part, through crosstalk between adipose tissue (AT) and the brain. AT releases small extracellular vesicles (sEV) that can cross the blood–brain barrier (BBB) and modulate multiple pathophysiological pathways, including BBB function; however, this has never been ...
Shalini Mishra, Yixin Su, Sangeeta Singh, Ashish Kumar, Fang‐Chi Hsu, Gagan Deep, Tina E. Brinkley   +6 more
wiley   +1 more source

Neurovascular pericytes are susceptible to infection by JC polyomavirus. [PDF]

J Virol
O'Hara BA, Garabian K, Yuan W, Atwood WJ, Haley SA.   +4 more
europepmc   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Models of cardiomyocyte–non‐myocyte electrical interactions

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiomyocyte–non‐myocyte (CM–NM) electrotonic coupling. Left: conceptual contact‐based interactions between CM and other NM via connexin (Cx) proteins. Three basic scenarios are proposed: (i) ‘zero‐sided coupling’ where there are no electrical connections between CM and NM, (ii) ‘single‐sided coupling’ where NM are connected to ...
Ana Simon‐Chica, Axel Loewe, Peter Kohl   +2 more
wiley   +1 more source

Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension. [PDF]

Cardiovasc Res
Cober ND, McCourt E, Godoy RS, Deng Y, Schlosser K, Qamsari ES, Azami J, Salehisiavashani E, Cook DP, Lemay SE, Klouda T, Yuan K, Bonnet S, Stewart DJ.   +13 more
europepmc   +1 more source

Ultrastructure of astrocytes using volume electron microscopy: A scoping review

The Journal of Physiology, EarlyView.
Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini, Maria Fernanda Veloz Castillo, Francesco Biancardi, Ferdinando Di Cunto, Pierre J. Magistretti, Alessandro Vercelli, Marco Agus, Corrado Calì   +7 more
wiley   +1 more source