Results 11 to 20 of about 1,061 (171)

Chemoselective additions of thiophenol to carvone and perillaldehyde

open access: yesChemInform, 2002
Depending on the reaction conditions addition of thiophenol can be directed to either of the two C=C-double bonds of the monoterpenes carvone and perillaldehyde.
Smitt, Olof, Högberg, Hans-Erik,
core   +11 more sources

Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines [PDF]

open access: yesPharmaceutics, 2020
We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for ...
Antonello Santini   +2 more
exaly   +4 more sources

Antifungal Activity and Mechanism of Perillaldehyde against Penicillium citrinum, a Major Fungal Pathogen of Myrica rubra [PDF]

open access: yesShipin Kexue, 2023
Perillaldehyde is a green and safe natural antibacterial substance extracted from perilla leaves, which is also used as a food additive in food production.
LI Ruiyi, WU Weijie, FANG Xiangjun, CHEN Hangjun, HAN Yanchao, NIU Ben, CHEN Huizhi, GAO Haiyan
doaj   +3 more sources

In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde [PDF]

open access: yesGenes and Environment, 2021
Background Perillaldehyde and cinnamaldehyde are natural substances found in plants that are used as flavoring ingredients. Due to the α,β-unsaturated aldehydes in their structures, these compounds are expected to be DNA reactive. Indeed, several reports
Masamitsu Honma   +5 more
doaj   +3 more sources

Inhibitory Effects and Mechanisms of Perilla Essential Oil and Perillaldehyde against Chestnut Pathogen Botryosphaeria dothidea [PDF]

open access: yesJournal of Fungi
Botryosphaeria dothidea, a notorious plant pathogen, is responsible for causing chestnut rot during postharvest storage. This research aimed to assess the antifungal properties of perilla essential oil (PEO) and perillaldehyde (PAE) against B.
Qi Zeng   +6 more
doaj   +3 more sources

Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response [PDF]

open access: yesFrontiers in Immunology, 2021
Cyclic GMP-AMP synthase (cGAS), serving as a primary sensor of intracellular DNA, is essential to initiate anti-microbial innate immunity. Inappropriate activation of cGAS by self-DNA promotes severe autoinflammatory diseases such as Aicardi–Goutières ...
Lei Chu   +10 more
doaj   +3 more sources

Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy [PDF]

open access: yesBiomedicine & Pharmacotherapy, 2022
Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of chemoresistance, which can arise towards apoptosis. This work elucidates the anticancer mechanisms evoked by perillaldehyde, a monoterpenoid isolated from ...
Turrini, Eleonora   +10 more
core   +5 more sources

Nutrients and Main Secondary Metabolites Characterizing Extracts and Essential Oil from Fruits of Ammodaucus leucotrichus Coss. & Dur. (Western Sahara)

open access: yesMolecules, 2022
The ethnobotany of the Sahrawi people considers various species of plants and crude drugs as food, cooking spices and traditional health remedies. From among these, the fruits of Ammodaucus leucotrichus Coss. & Dur.
Mohamed Lamin Abdi Bellau   +8 more
doaj   +2 more sources

Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2018
The skin covers the outer surface of the body, so the epidermal keratinocytes within it are susceptible to reactive oxygen species (ROS) generated by environmental pollutants such as benzo(a)pyrene (BaP), a potent activator of aryl hydrocarbon receptor ...
Hiroshi Uchi   +6 more
core   +4 more sources

In Vitro Investigation of the Anticancer Properties of Ammodaucus Leucotrichus Coss. & Dur. [PDF]

open access: yesPharmaceuticals, 2022
Little is known about the pharmacological activity of Ammodaucus leucotrichus Coss. & Dur., a small annual species that grows in the Saharan and sub-Saharan countries. In the present study, we investigated whether the standardized ethanolic extract of A.
Monia Lenzi   +12 more
doaj   +3 more sources

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