Chemoselective additions of thiophenol to carvone and perillaldehyde
Depending on the reaction conditions addition of thiophenol can be directed to either of the two C=C-double bonds of the monoterpenes carvone and perillaldehyde.
Smitt, Olof, Högberg, Hans-Erik,
core +11 more sources
Perillaldehyde 1,2-epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and In Vitro Cytotoxicity Profile in MCF-7 Cell Lines [PDF]
We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for ...
Antonello Santini +2 more
exaly +4 more sources
Antifungal Activity and Mechanism of Perillaldehyde against Penicillium citrinum, a Major Fungal Pathogen of Myrica rubra [PDF]
Perillaldehyde is a green and safe natural antibacterial substance extracted from perilla leaves, which is also used as a food additive in food production.
LI Ruiyi, WU Weijie, FANG Xiangjun, CHEN Hangjun, HAN Yanchao, NIU Ben, CHEN Huizhi, GAO Haiyan
doaj +3 more sources
In vivo and in vitro mutagenicity of perillaldehyde and cinnamaldehyde [PDF]
Background Perillaldehyde and cinnamaldehyde are natural substances found in plants that are used as flavoring ingredients. Due to the α,β-unsaturated aldehydes in their structures, these compounds are expected to be DNA reactive. Indeed, several reports
Masamitsu Honma +5 more
doaj +3 more sources
Inhibitory Effects and Mechanisms of Perilla Essential Oil and Perillaldehyde against Chestnut Pathogen Botryosphaeria dothidea [PDF]
Botryosphaeria dothidea, a notorious plant pathogen, is responsible for causing chestnut rot during postharvest storage. This research aimed to assess the antifungal properties of perilla essential oil (PEO) and perillaldehyde (PAE) against B.
Qi Zeng +6 more
doaj +3 more sources
Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response [PDF]
Cyclic GMP-AMP synthase (cGAS), serving as a primary sensor of intracellular DNA, is essential to initiate anti-microbial innate immunity. Inappropriate activation of cGAS by self-DNA promotes severe autoinflammatory diseases such as Aicardi–Goutières ...
Lei Chu +10 more
doaj +3 more sources
Perillaldehyde is a new ferroptosis inducer with a relevant clinical potential for acute myeloid leukemia therapy [PDF]
Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of chemoresistance, which can arise towards apoptosis. This work elucidates the anticancer mechanisms evoked by perillaldehyde, a monoterpenoid isolated from ...
Turrini, Eleonora +10 more
core +5 more sources
The ethnobotany of the Sahrawi people considers various species of plants and crude drugs as food, cooking spices and traditional health remedies. From among these, the fruits of Ammodaucus leucotrichus Coss. & Dur.
Mohamed Lamin Abdi Bellau +8 more
doaj +2 more sources
Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes [PDF]
The skin covers the outer surface of the body, so the epidermal keratinocytes within it are susceptible to reactive oxygen species (ROS) generated by environmental pollutants such as benzo(a)pyrene (BaP), a potent activator of aryl hydrocarbon receptor ...
Hiroshi Uchi +6 more
core +4 more sources
In Vitro Investigation of the Anticancer Properties of Ammodaucus Leucotrichus Coss. & Dur. [PDF]
Little is known about the pharmacological activity of Ammodaucus leucotrichus Coss. & Dur., a small annual species that grows in the Saharan and sub-Saharan countries. In the present study, we investigated whether the standardized ethanolic extract of A.
Monia Lenzi +12 more
doaj +3 more sources

