Results 61 to 70 of about 269,754 (267)
Introduction There are two main data sources for perinatal data in Ontario, Canada: the BORN BIS and CIHI-DAD. Such databases are used for perinatal health surveillance and research, and to guide health care related decisions.
Elizabeth Darling +2 more
doaj +1 more source
Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel +12 more
wiley +1 more source
Perinatal e-screening and clinical decision support: the Maternity Case-finding Help Assessment Tool (MatCHAT) [PDF]
INTRODUCTIONScreening tools assist primary care clinicians to identify mental health, addiction and family violence problems. Electronic tools have many advantages, but there are none yet available in the perinatal context. AIMTo assess the acceptability
Felicity Goodyear-Smith +5 more
doaj
Perinatal infections and perinatal outcomes
Preterm premature rupture of the membranes (PPROM) is a condition that can lead to maternal, fetal, and neonatal morbidity and mortality. It happens in 3% of pregnancies and is the cause of one-third of the total number of preterm births. An infection has been implicated both as a common underlying cause and a consequence of PPROM.
openaire +1 more source
Essential embryology for the Canadian pathologists’ assistant
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci +4 more
wiley +1 more source
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
BackgroundPrevalence of marijuana and cannabinoid use is increasing among reproductive-age women. There are uncertainties regarding long-term impacts of marijuana and/or cannabinoid exposure among pregnant women and their offspring.
Deepthi S. Varma +3 more
doaj +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
IntroductionPerinatal individuals are at an increased risk of experiencing psychological distress, which often manifests in a combination of co-occurring symptoms of anxiety, depression, and stress.
Alissa Papadopoulos +4 more
doaj +1 more source

