Results 71 to 80 of about 274,238 (267)

Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation

open access: yesAutism Research, EarlyView.
ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl   +6 more
wiley   +1 more source

Perinatal e-screening and clinical decision support: the Maternity Case-finding Help Assessment Tool (MatCHAT) [PDF]

open access: yesJournal of Primary Health Care, 2020
INTRODUCTIONScreening tools assist primary care clinicians to identify mental health, addiction and family violence problems. Electronic tools have many advantages, but there are none yet available in the perinatal context. AIMTo assess the acceptability
Felicity Goodyear-Smith   +5 more
doaj  

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove   +4 more
wiley   +1 more source

Willingness of pregnant and postpartum women who use marijuana and/or cannabidiol to participate with their offspring in long-term cohort studies: an exploratory study

open access: yesFrontiers in Psychiatry
BackgroundPrevalence of marijuana and cannabinoid use is increasing among reproductive-age women. There are uncertainties regarding long-term impacts of marijuana and/or cannabinoid exposure among pregnant women and their offspring.
Deepthi S. Varma   +3 more
doaj   +1 more source

Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar   +6 more
wiley   +1 more source

Coping styles, strategies and psychological distress amongst perinatal individuals during the COVID-19 pandemic: a rapid review

open access: yesFrontiers in Global Women's Health
IntroductionPerinatal individuals are at an increased risk of experiencing psychological distress, which often manifests in a combination of co-occurring symptoms of anxiety, depression, and stress.
Alissa Papadopoulos   +4 more
doaj   +1 more source

Endocrine And Metabolic Adaptations Of Calves To Extra-Uterine Life

open access: yesActa Veterinaria, 2015
The transition from intra- to extra-uterine life is one of the greatest physiological challenges that occur in the life of animals. Immediately after birth, newborn calves have to adapt to new environmental and feeding conditions.
Danijela Kirovski
doaj   +1 more source

Perinatal Nephropathies [PDF]

open access: yesEnvironmental Health Perspectives, 1976
The purpose of this paper is to review the development of the mammalian kidney and to assess the influence that various perinatal manipulations may have on the developmental process either morphologically or functionally. Immature kidneys in general have less functional capacity than adult kidneys and a low rate of glomerular filtration, perhaps ...
openaire   +2 more sources

Codeine toxicity via breast Milk: Can this occur and implications for opiate therapy in children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Codeine is commonly used in combination analgesic products. The use of codeine during breastfeeding can rarely be associated with serious adverse effects related to genetic polymorphisms affecting codeine's metabolism and disposition. Clinicians treating infants of breastfeeding mothers should be aware of this rare but potentially serious complication.
Michael Rieder
wiley   +1 more source

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