Results 111 to 120 of about 10,499,951 (250)
Regulation of long-term memory by a few clock neurons in Drosophila
Biophysics and PhysicobiologyIdentification of the neural circuits in the brain regulating animal behavior and physiology is critical for understanding brain functions and is one of the most challenging goals in neuroscience research.
Rei Shirakawa +2 more
doaj +1 more source
Substring Counting with Insertions
AlgorithmsSubstring counting is a classical algorithmic problem with numerous solutions that achieve linear time complexity. In this paper, we address a variation of the problem where, given three strings p, t, and s, we are interested in the number of occurrences
Janez Brank, Tomaž Hočevar
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Long-period orbital climate forcing. Cyclostratigraphic studies of Cenozoic continental and marine successions in Europe. Geologica Ultraiectina (297) [PDF]
, 2008 Orbital climate forcing is well-known for its strong impact on Earth’s climate as for example the switching from glacial to inter-glacial states in the Late Pleistocene.
Abels, H.A. +5 more
core +1 more source
Premières réalisations de la période dans le roman de chevalerie : Amadis en français et en allemand
Cahiers d’Études GermaniquesThe romance of chivalry is a genre rather at odds with the period. Nevertheless, forms of complete argumentative movements, marked by syntactic complexity and programming the revelation of information, can be discerned in Des Essarts’ translation of the ...
Pascale MOUNIER, Delphine PASQUES
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Cahiers d’Études GermaniquesWhat forms do periods take in French discourse, with what uses and effects? The study of a particular category of discourse allows us to develop this reflection: parliamentary remonstrances, which constitute an institutional genre of oratory whose form ...
Sophie Hache
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Three Spreadsheet Models Of A Simple Pendulum
Spreadsheets in Education, 2008 The paper gives three spreadsheet models of simple pendulum motion. In two of them, the graph of the pendulum angle is drawn upon the exact integral solution using numeric integration – the simpler model only uses spreadsheet functions, the general model
Jan Benacka
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source