Results 81 to 90 of about 172,494 (276)
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Stability and control of compressible flows over a surface with concave-conves curvature [PDF]
The active control of spatially unstable disturbances in a laminar, two-dimensional, compressible boundary layer over a curved surface is numerically simulated. The control is effected by localized time-periodic surface heating.
Bayliss, A. +3 more
core +1 more source
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Effects of Oscillating Plates on the Plane Mixing Layer, Its Developing Region and Jet [PDF]
Effects of oscillating plates on the plane mixing layer, its developing region and jet were experimentally Investigated. The flow was formed by the jet issued from the two-dimensional nozzle and surrounding quiescent air.
Ichimiya, M.
core +1 more source
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
This paper presents a robust speed regulation and control of a permanent magnet synchronous motor (PMSM). A linear quadratic regulator (LQR) based state feedback controller was developed to achieve a successful suppression of periodic disturbance of ...
Crescent Onyebuchi Omeje +2 more
doaj +1 more source
Numerical and Experimental Validation of Mixing Efficiency in Periodic Disturbance Mixers. [PDF]
López RR +5 more
europepmc +1 more source

