Results 151 to 160 of about 241,774 (311)

Bifurcation from a normally degenerate manifold

open access: yes, 2010
Local bifurcation theory typically deals with the response of a degenerate but isolated equilibrium state or periodic orbit of a dynamical system to perturbations controlled by one or more independent parameters, and characteristically uses tools from ...
Chillingworth, D. R. J.   +2 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Computing v 1 -periodic homotopy groups of spheres and some compact Lie groups

open access: yes, 1995
this paper, we present an account of the principal methods which have been used to compute the v 1 -periodic homotopy groups of spheres and many compact simple Lie groups. The two main tools have been J-homology and the unstable Novikov spectral sequence
Donald M. Davis
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

3-Primary v_1-Periodic Homotopy Groups of E_7

open access: yes, 1998
. In this paper we compute the 3-primary v1 -periodic homotopy groups of the exceptional Lie group E 7 . This represents the next stage in the author's goal of calculating the v1 -periodic homotopy groups of all compact simple Lie groups (at least ...
Donald M. Davis
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

v_1 -Periodic Homotopy Groups of Sp(n)

open access: yes, 1995
this paper we calculate the 2-primary v 1 -periodic homotopy groups of the symplectic groups Sp(n). The proof utilizes new methods of calculating the unstable Novikov spectral sequence.
Martin Bendersky   +3 more
core  

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