Results 111 to 120 of about 231,424 (276)

The molecular mechanism by which heat stress during the grain filling period inhibits maize grain filling and reduces yield

Frontiers in Plant Science
High temperatures significantly impair plant growth and development by restricting maize grain filling; however, the molecular mechanisms underlying heat stress remain poorly understood. In this study, 350 maize inbred lines were evaluated under field conditions, leading to the identification of heat-tolerant Zheng58 and heat-sensitive Qi319.
Xiaohu Li, Shilin Zhuge, Jiyuan Du, Peng Zhang, Xingyu Wang, Tianjian Liu, Donghui Li, Haoran Ma, Xinzheng Li, Yongxin Nie, Changjian Liao, Haiping Ding, Zhiming Zhang   +12 more
openaire   +2 more sources

The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad, Taimoon Rasheed, Momina Riaz Siddiqui, Hamza Hamid, Marwah Bintay Khalid, Haroon Shabbir, Besher Shami, Abdullah, Syed Ijlal Ahmed   +8 more
wiley   +1 more source

Integrated Transcriptomic and Proteomic Analysis Reveals Molecular Mechanisms of the Cold Stress Response during the Overwintering Period in Blueberries (Vaccinium spp.)

Plants
In China, the Liaodong Peninsula is an important growing area for blueberries because of the high organic matter content in the soil, the abundance of light, and the large temperature difference between day and night. However, the low temperature and relative humidity of the air during the winter and early spring in the Liaodong Peninsula are the main ...
Xin Wei, Hongguang Wang, Dan Guo, Baisong Wang, Xiao Zhang, Jian Wang, Youchun Liu, Xingdong Wang, Cheng Liu, Wenxuan Dong   +9 more
openaire   +3 more sources

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

A theoretical method to analyze the effect of stress distribution on compressive strength of periodic lattices

Materials & Design
The lattice structures or lattice metamaterials have been widely used in aerospace and medical fields, and the mechanical properties were mostly evaluated based on simulated stress distribution.
Zulei Liang, Yansong Meng, Jiaxi Zhao, Zhanggang Sun, Yanhua Guo, Jie Xia, Hui Chang, Lian Zhou, I.V. Alexandrov   +8 more
doaj  

Mechanical properties of AlSi10Mg lattice structures fabricated by selective laser melting

Materials & Design, 2020
Al alloy porous structures have potential application in industries such as light aerospace and some heat exchanger products. A particular advantage of selective laser melting (SLM) over conventional manufacturing processes is its ability to fabricate ...
Zhong-hua Li, Yun-fei Nie, Bin Liu, Ze-zhou Kuai, Miao Zhao, Fei Liu   +5 more
doaj  

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Influence of deformed primitive architecture on mechanical behavior of artificial porous meniscus

Materials & Design, 2020
Polycarbonate urethane (PCU) has emerged as a suitable material for artificial meniscus replacement after meniscectomy. However, the commercial PCU meniscal replacements could not reproduce native meniscus performance until now. The aim of this paper was
Li-ya Zhu, Ming Cheng, Wen-chen Sun, Ji-quan Yang, Lan Li, Qing Jiang   +5 more
doaj  

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri, Manuel Meraz, Hamraz Mokri, Sajesh K Veettil, Karn Wijarnpreecha, Naomi Schlesinger, Arthur Kavanaugh, Nathorn Chaiyakunapruk   +7 more
wiley   +1 more source