Results 61 to 70 of about 1,473,692 (365)

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Level spacings and periodic orbits [PDF]

Physical Review E, 2001
Starting from a semiclassical quantization condition based on the trace formula, we derive a periodic-orbit formula for the distribution of spacings of eigenvalues with k intermediate levels. Numerical tests verify the validity of this representation for the nearest-neighbor level spacing (k=0). In a second part, we present an asymptotic evaluation for
openaire   +3 more sources

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Period-Multiplying Bifurcations in the Gravitational Field of Asteroids

Aerospace
Periodic orbit families around asteroids serve as potential trajectories for space probes, mining facilities, and deep space stations. Bifurcations of these families provide additional candidate orbits for efficient trajectory design around asteroids ...
P. Rishi Krishna, Joel George Manathara
doaj   +1 more source

Application of the Trace Formula in Pseudointegrable Systems

, 2006
We apply periodic-orbit theory to calculate the integrated density of states $N(k)$ from the periodic orbits of pseudointegrable polygon and barrier billiards.
H. P. Baltes, H.-J. Stöckmann, Jesper Mellenthin, M. L. Mehta, Stefanie Russ   +4 more
core   +1 more source

Periodic orbit description of tunneling in symmetric and asymmetric double-well potentials

, 1979
Semiclassical periodic orbit theory is applied to the double-well eigenvalue problem to show how this unified approach describes the quite different character of the level splitting (in the case of symmetric wells) and level shifts (in the asymmetric ...
W. Miller
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Precessing and periodic motions around a black-bounce/traversable wormhole

European Physical Journal C: Particles and Fields, 2020
We investigate precessing and periodic geodesic motions of timelike particles around a black-bounce/traversable wormhole. After obtaining its semi-classic and relativistic periastron advance, we find a preliminary bound on the scale length of such a ...
Tian-Yi Zhou, Yi Xie
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Composition law of cardinal order permutations

, 2009
In this paper the theorems that determine composition laws for both cardinal ordering permutations and their inverses are proven. So, the relative positions of points in a hs-periodic orbit become completely known as well as in which order those points ...
A. González Gómez, Alsedá, Amigó, Amigó, Amigó, Amigó, Amigó, Bai-Lin, Bandt, Blokh, Blokh, Collet, de Melo, Derrida, Feigenbaum, Feigenbaum, Gilmor, Hall, Ingram, Jesús San Martín, M. José Moscoso, Metropolis, Milnor, San Martín, San Martín, San Martín, Sharkovsky, Stefan, Wang, Xie, Zheng, Zunino   +31 more
core   +1 more source