Results 61 to 70 of about 645,356 (284)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
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Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
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FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
GEOPHYSICAL EFFECTS OF THE EARTH'S MONTHLY MOTION
Odessa Astronomical Publications, 2013 The generation of a lunar tidal force is a major geophysical effect of the Earth's monthly motion. It is shown that synoptic processes vary simultaneously with tidal oscillations of the Earth's rotation rate and weather exhibits changes near their ...
N. S. Sidorenkov, T. S. Zhigailo
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Моделирование и анализ информационных систем, 2015 We consider a finite-dimensional model of phase oscillators with inertia in the case of star configuration of coupling. The system of equations is reduced to a nonlinearly coupled system of pendulum equations.
V. N. Belykh +2 more
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The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
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Mathematics, 2019 In our paper, we propose a single population Smith model with continuous delay and impulsive state feedback control. The application in pest management of this model is investigated.
Zhenzhen Shi, Yaning Li, Huidong Cheng
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Periodic solutions with long period for the Mackey–Glass equation
Electronic Journal of Qualitative Theory of Differential Equations, 2020 The limiting version of the Mackey–Glass delay differential equation $x'(t)=-ax(t)+bf(x(t-1))$ is considered where $a,b$ are positive reals, and $f(\xi)=\xi$ for $\xi\in[0,1)$, $f(1)=1/2$, and $f(\xi)=0$ for $\xi> 1$.
Tibor Krisztin
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source