Results 81 to 90 of about 1,506,135 (383)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Orbit Determination Error Analysis for the KOMPSAT [PDF]
Journal of Astronomy and Space Sciences, 1998 Orbit error analysis was performed for the GPS navigation solutions and ground station tracking data of the KOMPSAT (Korea Multi-Purpose SATellite), which will be launched in 1999 for cartography of Korean peninsula as main mission. A least square method
Jeong-Sook Lee, Byoung-Sun Lee
doaj
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Periodic solutions with long period for the Mackey–Glass equation
Electronic Journal of Qualitative Theory of Differential Equations, 2020 The limiting version of the Mackey–Glass delay differential equation $x'(t)=-ax(t)+bf(x(t-1))$ is considered where $a,b$ are positive reals, and $f(\xi)=\xi$ for $\xi\in[0,1)$, $f(1)=1/2$, and $f(\xi)=0$ for $\xi> 1$.
Tibor Krisztin
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Unstable periodic orbits and attractor of the barotropic ocean model [PDF]
Nonlinear Processes in Geophysics, 1998 A numerical method for detection of unstable periodic orbits on attractors of nonlinear models is proposed. The method requires similar techniques to data assimilation. This fact facilitates its implementation for geophysical models. ...
E. Kazantsev
doaj
Non-contractible periodic orbits in Hamiltonian dynamics on tori
, 2017 We show that the presence of one non-degenerate, non-contractible periodic orbit of a Hamiltonian on the standard symplectic torus implies the existence of infinitely many simple non-contractible periodic orbits.Comment: 10 pages, minor revision ...
Orita, Ryuma
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
A model for aperiodicity in earthquakes [PDF]
Nonlinear Processes in Geophysics, 2008 Conditions under which a single oscillator model coupled with Dieterich-Ruina's rate and state dependent friction exhibits chaotic dynamics is studied. Properties of spring-block models are discussed.
B. Erickson, B. Birnir, D. Lavallée
doaj