Results 71 to 80 of about 107,633 (324)
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
Displaced solar sail orbits : dynamics and applications [PDF]
, 2010 We consider displaced periodic orbits at linear order in the circular restricted Earth-Moon system, where the third massless body is a solar sail. These highly non-Keplerian orbits are achieved using an extremely small sail acceleration.
McInnes, Colin R., Simo, Jules
core +1 more source
On the existence of a new type of periodic and quasi-periodic orbits for twist maps of the torus
, 2002 We prove that for a large and important class of $C^1$ twist maps of the torus periodic and quasi-periodic orbits of a new type exist, provided that there are no rotational invariant circles (R.I.C's).
Zanata, S Addas
core +1 more source
Application of the diffraction trace formula to the three disk scattering system [PDF]
, 1996 The diffraction trace formula ({\em Phys. Rev. Lett.} {\bf 73}, 2304 (1994)) and spectral determinant are tested on the open three disk scattering system. The system contains a generic and exponentially growing number of diffraction periodic orbits.
Rosenqvist, Per E. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley +1 more source
A method to find unstable periodic orbits for the diamagnetic Kepler Problem
, 2000 A method to determine the admissibility of symbolic sequences and to find the unstable periodic orbits corresponding to allowed symbolic sequences for the diamagnetic Kepler problem is proposed by using the ordering of stable and unstable manifolds.
Cvitanovic P +7 more
core +1 more source
Periodic orbits in polygonal billiards [PDF]
Pramana, 1997 We review some properties of periodic orbit families in polygonal billiards and discuss in particular a sum rule that they obey. In addition, we provide algorithms to determine periodic orbit families and present numerical results that shed new light on the proliferation law and its variation with the genus of the invariant surface.
openaire +3 more sources
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Rational Orbits around Charged Black Holes
, 2010 We show that all eccentric timelike orbits in Reissner-Nordstr\"{o}m spacetime can be classified using a taxonomy that draws upon an isomorphism between periodic orbits and the set of rational numbers.
Janna Levin +3 more
core +1 more source