Results 131 to 140 of about 9,489,153 (244)

On second order periodic boundary-value problems with upper and lower solutions in the reversed order

Electronic Journal of Differential Equations, 2006
In this paper, we study the differential equation with the periodic boundary value $$displaylines{ u''(t)=f(t, u(t), u'(t)),quad tin [0, 2pi]cr u(0)=u(2pi), quad u'(0)=u'(2pi).
Haiyin Gao, Shiyou Weng, Daqing Jiang, Xuezhang Hou   +3 more
doaj  

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

A condition on the potential for the existence of doubly periodic solutions of a semi-linear fourth-order partial differential equation

Electronic Journal of Differential Equations, 2000
We study the existence of solutions to the fourth order semi-linear equation $Delta ^2u=g(u)+h(x)$. We show that there is a positive constant $C_*$, such that if $g(xi )xi geq 0$ for $|xi |geq xi _0$ and $limsup _{|xi |o infty } 2G(xi )/xi ...
Chen Chang
doaj  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Existence of multiple periodic solutions for second-order discrete Hamiltonian systems with partially periodic potentials

Electronic Journal of Differential Equations, 2016
In this article, we use critical point theory to obtain multiple periodic solutions for second-order discrete Hamiltonian systems, when the nonlinearity is partially periodic and its gradient is linearly and sublinearly bounded.
Qin Jiang, Sheng Ma, Zhihua Hu
doaj  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Almost periodic solutions of higher order differential equations on Hilbert spaces

Electronic Journal of Differential Equations, 2010
We find necessary and sufficient conditions for the differential equation $$ u^{(n)}(t) = Au(t)+f(t), quad tin mathbb{R} $$ to have a unique almost periodic solution. Some applications are also given.
Lan Thanh Nguyen
doaj  

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Collocation methods for a class of second order initial value problems with oscillatory solutions [PDF]

, 1993
We derive and analyse two families of multistep collocation methods for periodic initial-value problems of the form y" = f(x, y); y((^x)o) = yo, y(^1)(xo) = zo involving ordinary differential equations of second order in which the first derivative ...
Booth, Andrew S.
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source