Results 81 to 90 of about 9,926,750 (356)
Periodic solutions for a class of second order differential equations
New results about the existence of periodic solutions for second order differential equations are provided. The method of proof relies on the Schauder's fixed point theorem. Some examples are presented to illustrate the main results.
Weibing Wang, Yan Luo
doaj +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Rotating periodic solutions for second order systems with Hartman-type nonlinearity
In this paper, by a constructive proof based on the homotopy continuation method, we prove that the second order system x″=g(t,x) $x''=g(t,x)$ admits rotating periodic solutions with form u(t+T)=Qu(t) $u(t+T)=Qu(t)$ for any orthogonal matrix Q when the ...
Jian Li, Xiaojun Chang, Yong Li
doaj +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Rotating periodic solutions of second order dissipative dynamical systems
This paper is devoted to the following second order dissipative dynamical system \begin{equation*} u''+cu'+ \nabla g(u)+h(u)=e(t) ~\mbox{in}~\mathbb{R}^n.
Xiaojun Chang, Yong Li
semanticscholar +1 more source
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Multiplicity of Periodic Solutions for a Higher Order Difference Equation
We study a higher order difference equation. By Lyapunov-Schmidt reduction methods and computations of critical groups, we prove that the equation has four M-periodic solutions.
Ronghui Hu
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source

