Results 81 to 90 of about 503,079 (239)
Permanent muscle weakness in hypokalemic periodic paralysis
, 2020 ObjectiveTo map the phenotypic spectrum in 55 individuals with mutations in CACNA1S known to cause hypokalemic periodic paralysis (HypoPP) using medical history, muscle strength testing, and muscle MRI.MethodsAdults with a mutation in CACNA1S known to ...
Fornander, Freja +9 more
core +1 more source
Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment
Annals of Neurology, EarlyView.Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring +18 more
wiley +1 more source
Annals of Neurology, EarlyView.Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau +8 more
wiley +1 more source
THYROTOXIC HYPOKALEMIC PERIODIC PARALYSIS PRESENTING WITH PARAPARESIS
, 2013 Thyrotoxic hypokalemic periodic paralysis (THPP) is a rare hyperthyroidism-related endocrine disorder seen predominantly in men of Asian origin. The main characteristics of the disease are hyperthyroidism, hypokalemia, muscle weakness and acute paralysis.
Dogru, Cumali +4 more
core +2 more sources
Thyrotoxic Periodic Paralysis: The Report of Four Cases
Endocrinology Research and Practice, 2022 The syndrome of hypokalaemic paralysis represents a heterogeneous group of disorders characterized clinically by hypokalaemia and acute systemic weakness.
Ahmet Kaya +2 more
doaj +2 more sources
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To prospectively investigate subjective anterior groin pain, patient‐reported outcome measures, complications, reoperation rates, and hip flexion strength after arthroscopic iliopsoas fractional lengthening. Methods From 2023 to 2025, patients with persistent groin pain after total hip arthroplasty refractory to conservative management ...
Brandon Cabarcas +7 more
wiley +1 more source
Thyrotoxic Hypokalemic Periodic Paralysis: A Case Report
, 2014 Hypokalemic periodic paralysis is a rare disorder characterized by reversible attacks of muscle weakness accompanied by episodic hypokalemia. The most common causes of hypokalemic periodic paralysis (HPP) are familial periodic paralysis, thyrotoxic ...
Karakılıç, Ersen +6 more
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British Journal of Clinical Pharmacology, EarlyView.Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar +6 more
wiley +1 more source
Acetazolamide in Hypokalemic Periodic Paralysis
Pediatric Neurology Briefs, 2000 The mechanism of action of acetazolamide in the K-deficient diet rat, an animal model of human hypokalemic periodic paralysis (hypoPP), was investigated at the University of Bari, Italy.
J Gordon Millichap
doaj +1 more source
, 2017 Thyrotoxic periodic paralysis (TPP) is characterized by abrupt onset of hypokalemia and paralysis secondary to thyrotoxicosis (1). The hypokalemia is a result of intracellular shift of potassium due to sensitization of the sodium/potassium (Na+-K ...
Alzahrani, Talal +5 more
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