Results 61 to 70 of about 8,136,999 (366)

A Periodic Analog of the Schwarzschild Solution

, 1994
We construct a new exact solution of Einstein's equations in vacuo in terms of Weyl canonical coordinates. This solution may be interpreted as a black hole in a space-time which is periodic in one direction and which behaves asymptotically like the ...
Korotkin, D., Nicolai, H.
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Periodic solutions of spatially periodic hamiltonian systems

Journal of Differential Equations, 1992
Abstract : This work is concerned with the study of existence and multiplicity of periodic solutions of Hamiltonian systems of ordinary differential equations z=J(Hz(z,t) + f(t)) when the Hamiltonian H(z,t) = H(p,q,t) is periodic in the variable q and superlinear in the variable p.
Patricio Felmer, Patricio Felmer
openaire   +2 more sources

Relative Periodic Solutions of the Complex Ginzburg-Landau Equation

, 2005
A method of finding relative periodic orbits for differential equations with continuous symmetries is described and its utility demonstrated by computing relative periodic solutions for the one-dimensional complex Ginzburg-Landau equation (CGLE) with ...
Dang‐Vu H., Lan Yueheng, Levenberg Kenneth, Michael T. Heath, Miller Willard, Philip Boyland, Robert D. Moser, Vanessa López   +7 more
core   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Spatial chaos in weakly dispersive and viscous media: a nonperturbative theory of the driven KdV-Burgers equation

, 1996
The asymptotic travelling wave solution of the KdV-Burgers equation driven by the long scale periodic driver is constructed. The solution represents a shock-train in which the quasi-periodic sequence of dispersive shocks or soliton chains is interspersed
Aubry, Devaney, Farmer, Fedorjuk, Feigenbaum, Gurevich, Hada, Kantz, Karpman, Kennel, Lorenz, M.A Malkov, Malkov, Malkov, Malkov, McCauley, Moriguchi, Pomeau, Rogister, Sagdeev, Taniuti, Whitham, Whitham   +22 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

On periodic solutions in the Whitney's inverted pendulum problem

, 2018
In the book `What is Mathematics?' Richard Courant and Herbert Robbins presented a solution of a Whitney's problem of an inverted pendulum on a railway carriage moving on a straight line.
Srzednicki, Roman
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source