From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
On computing inner-outer factorizations of periodic systems [PDF]
A numerically reliable state space algorithm is proposed for computing inner-outer factorizations of causal periodic descriptor systems. The main computational ingredients are the computation of a special condensed Kronecker-like form of periodic ...
Varga, Andreas, Andreas Varga
core +1 more source
On the solutions of a second order difference equation [PDF]
In this paper, we discuss the global behavior of all solutions of the difference equation Xn+1 = XnXn-1 axn + bxn-1, n € N0, where a; b are real numbers and the initial conditions X-1, X0 are real numbers.
Abo-Zeid R.
doaj
We consider discrete models of the form xn+1=xnf(xn−1)+hn, where hn is a nonnegative p-periodic sequence representing stocking in the population, and investigate their dynamics. Under certain conditions on the recruitment function f(x), we give a compact
Ziyad AlSharawi
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Global Hopf bifurcation for two zooplankton-phytoplankton model with two delays
In this paper, we study the global existence of a bifurcating periodic solution for a two zooplankton-phytoplankton model with two delays. First, we demonstrate that the bifurcating periodic solution exists when one delay increases and the other delay ...
Renxiang Shi, Wenguo Yang
doaj +1 more source
Periodic Solutions of Quaternionic Riccati Equations with Periodic Coefficients
Abstract In this paper we study the conditions, under which the quaternionic Riccati equations have periodic solutions. The obtained result we compare with one recently obtained important one.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Positive Periodic Solution for Second-Order Nonlinear Differential Equations with Variable Coefficients and Mixed Delays. [PDF]
Dai Z, Du B.
europepmc +1 more source

