Results 81 to 90 of about 183,557 (259)

Positive periodic solutions for second-order neutral differential equations with functional delay

Electronic Journal of Differential Equations, 2012
We use Krasnoselskii's fixed point theorem to prove the existence of positive periodic solutions of the second-order nonlinear neutral differential equation $$ frac{d^2}{dt^2}x(t)+p(t)frac{d}{dt}x(t)+q(t)x(t) =cfrac{d}{dt}x(t-au(t))+f(t,h(x(t)),g(x ...
Ernest Yankson
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Periodic Systems Dependent on Parameters

Journal of Inequalities and Applications, 2010
This paper is concerned with a periodic system dependent on parameter. We study differentiability with respect to parameters of the periodic solution of the system. Applying a fixed point theorem and the results regarding parameters for C0-semigroups, we
Min He
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Periodic Solution of a Periodic Neutral Delay Equation

Journal of Mathematical Analysis and Applications, 1997
The paper deals with the existence of positive periodic solutions of the equation \[ N'(t)= N(t)\Biggl[a(t)- \sum^n_{j= 1}b_j(t)N(t-\sigma_j)- \sum^n_{j= 1}c_j(t)N'(t-\tau_j)\Biggr],\tag{1} \] where \(a\), \(b_j\), \(c_j\), \(j= 1,2,\dots, n\) are positive continuous functions periodic with period \(\omega>0\) and \(\sigma_j\), \(\tau_j\), \(j= 1,2 ...
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Existence of Periodic and Almost Periodic Solutions of Abstract Retarded Functional Difference Equations in Phase Spaces

Advances in Difference Equations, 2009
The existence of periodic, almost periodic, and asymptotically almost periodic of periodic and almost periodic of abstract retarded functional difference equations in phase spaces is obtained by using stability properties of a bounded solution.
Claudio Vidal
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Asymptotic periodicity in nonlinear coupled matrix Sylvester Volterra systems integro-dynamic system on arbitrary time domains

Boundary Value Problems
This paper presents both a periodic and an asymptotic periodic solution for coupled Sylvester matrix Volterra integro-dynamic systems on time scales. The vectorization operator first changes the Sylvester matrix into the Kronecker product of the system ...
Chintamaneni Harisha, Bhogapurapu Venkata Appa Rao, Ayyalappagari Sreenivasulu, Ahmad Aloqaily, Maryam G. Alshehri, Nabil Mlaiki   +5 more
doaj   +1 more source