Results 81 to 90 of about 8,371,508 (357)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Discrete Dynamics in Nature and Society, 2005 By using coincidence degree theory as well as a priori estimates and Lyapunov functional, we study the existence and global stability of periodic solution for discrete delayed high-order Hopfield-type neural networks.
Hong Xiang, Ke-Ming Yan, Bai-Yan Wang
doaj +1 more source
Periodic solutions of a class of indefinite singular differential equations [PDF]
, 2022 Zaitao Liang, Xiuqiang Zhang
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
On optimal periodic solution of differential equations
Journal of Kufa for Mathematics and Computer, 2018 this paper dedicated to the construction of solution of a three time scale periodic singular perturbed non-linear quadratic optimal control problem by using the direct method.
Methaq Hamza Geem
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Periodic wave-guides revisited: Radiation conditions, limiting absorption principles, and the space of bounded solutions [PDF]
, 2023 Andreas Kirsch, Ben Schweizer
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Abstract and Applied Analysis, 2013 We consider discrete models of the form xn+1=xnf(xn−1)+hn, where hn is a nonnegative p-periodic sequence representing stocking in the population, and investigate their dynamics. Under certain conditions on the recruitment function f(x), we give a compact
Ziyad AlSharawi
doaj +1 more source
Positive Periodic Solution for Second-Order Nonlinear Differential Equations with Variable Coefficients and Mixed Delays. [PDF]
Entropy (Basel), 2022 Dai Z, Du B.
europepmc +1 more source
C Stability of periodic solutions and solution schemes
Applied Mathematics Letters, 1988 This paper concerns the structural stability of a hyperbolic periodic orbit of an ordinary differential equation in \(\mathbb{R}^M\). This periodic orbit is an invariant circle for the time-\(T\)-map defined by the ODE in a neighbourhood of the orbit, and the time-\(T\)-map is an embedding of this neighbourhood in \(\mathbb{R}^M\). In the space of such
Pugh, Charles, Shub, Michael
openaire +2 more sources