Results 71 to 80 of about 766,070 (327)
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Equations of magnetohydrodynamics: periodic solutions [PDF]
Under suitable assumptions on external forces and currents the authors prove the existence of a time-periodic solution to a system of magneto- hydrodynamic equations for viscous incompressible and electrically conducting fluid. In the governing system of equations the displacement current is not neglected and in the Ohm law the Hall effect and ion slip
Milan Štědrý, Otto Vejvoda
openaire +2 more sources
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fundamental Solutions for Periodic Media
Necessity for the periodic fundamental solutions arises when the periodic boundary value problems should be analyzed. The latter are naturally related to problems of finding the homogenized properties of the dispersed composites, porous media, and media ...
Sergey V. Kuznetsov
doaj +1 more source
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
On Stability of Periodic Solutions of Lienard Type Equations
We use the Floquet theory to analyze the stability of periodic solutions of Lienard type equations under the asymptotic linear growth of restoring force in this paper.
Zijian Yin, Hongbin Chen
doaj +1 more source
On the application of Sturm's theorem to analysis of dynamic pull-in for a graphene-based MEMS model
A novel procedure based on the Sturm’s theorem for real-valued polynomials is developed to predict and identify periodic and non-periodic solutions for a graphene-based MEMS lumped parameter model with general initial conditions.
Omarov D. +3 more
doaj +1 more source

