Results 71 to 80 of about 773,939 (324)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

On Stability of Periodic Solutions of Lienard Type Equations

open access: yesDiscrete Dynamics in Nature and Society, 2017
We use the Floquet theory to analyze the stability of periodic solutions of Lienard type equations under the asymptotic linear growth of restoring force in this paper.
Zijian Yin, Hongbin Chen
doaj   +1 more source

On the application of Sturm's theorem to analysis of dynamic pull-in for a graphene-based MEMS model

open access: yesApplied and Computational Mechanics, 2018
A novel procedure based on the Sturm’s theorem for real-valued polynomials is developed to predict and identify periodic and non-periodic solutions for a graphene-based MEMS lumped parameter model with general initial conditions.
Omarov D.   +3 more
doaj   +1 more source

C Stability of periodic solutions and solution schemes

open access: yesApplied Mathematics Letters, 1988
This paper concerns the structural stability of a hyperbolic periodic orbit of an ordinary differential equation in \(\mathbb{R}^M\). This periodic orbit is an invariant circle for the time-\(T\)-map defined by the ODE in a neighbourhood of the orbit, and the time-\(T\)-map is an embedding of this neighbourhood in \(\mathbb{R}^M\). In the space of such
Pugh, Charles, Shub, Michael
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Periodic Solutions Generated by Impulses for State-Dependent Impulsive Differential Equation

open access: yesDiscrete Dynamics in Nature and Society, 2015
We study the existence of periodic solutions for a class of state-dependent impulsive differential systems via geometrical analysis methods. Our results show that these periodic solutions are generated by impulses.
Qizhen Xiao, Binxiang Dai
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

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