Results 81 to 90 of about 766,070 (327)

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

A new variational method with SPBC and many stable choreographic solutions of the Newtonian 4-body problem

open access: yes, 2013
After the existence proof of the first remarkably stable simple choreographic motion-- the figure eight of the planar three-body problem by Chenciner and Montgomery in 2000, a great number of simple choreographic solutions have been discovered ...
Ouyang, Tiancheng, Xie, Zhifu
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Periodic Solutions Generated by Impulses for State-Dependent Impulsive Differential Equation

open access: yesDiscrete Dynamics in Nature and Society, 2015
We study the existence of periodic solutions for a class of state-dependent impulsive differential systems via geometrical analysis methods. Our results show that these periodic solutions are generated by impulses.
Qizhen Xiao, Binxiang Dai
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Periodic solutions of spatially periodic hamiltonian systems

open access: yesJournal of Differential Equations, 1992
The existence of periodic solutions for Hamiltonian systems of ordinary differential equations (1) \(\dot z=J(H_ z(z,t)+f(t))\) is studied, where \(H: R^{2n}\times R\to R\) is of class \(C^ 1\) and is \(2\pi\)-periodic with respect to \(t\); \(f: R\to R\) is continuous and \(2\pi\)-periodic and \(J=\bigl({0 \atop I_ n} {-I_ n \atop 0}\bigr)\).
Patricio Felmer, Patricio Felmer
openaire   +2 more sources

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

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