Results 91 to 100 of about 25,043 (257)

Oscillatory dynamics in a model of vascular tumour growth - implications for chemotherapy

open access: yesBiology Direct, 2010
Background Investigations of solid tumours suggest that vessel occlusion may occur when increased pressure from the tumour mass is exerted on the vessel walls. Since immature vessels are frequently found in tumours and may be particularly sensitive, such
Maini PK, Owen MR, Stamper IJ, Byrne HM
doaj   +1 more source

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak   +11 more
wiley   +1 more source

Pressure swing adsorption process modeling using physics-informed machine learning with transfer learning and labeled data

open access: yesGreen Chemical Engineering
Pressure swing adsorption (PSA) modeling remains a challenging task since it exhibits strong dynamic and cyclic behavior. This study presents a systematic physics-informed machine learning method that integrates transfer learning and labeled data to ...
Zhiqiang Wu   +6 more
doaj   +1 more source

New Biologic and Small Molecule Therapies for Hidradenitis Suppurativa

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is an inflammatory skin disease that has historically been underdiagnosed and, until recently, under‐researched. Furthermore, the pathophysiology of HS is complex, and not fully understood. Just three biologic medications—adalimumab (anti‐TNF‐α), secukinumab (anti‐IL17A) and bimekizumab (anti‐IL17A/F) are licensed
Emily Pender   +2 more
wiley   +1 more source

From integral manifolds and metrics to potential maps

open access: yesAtti della Accademia Peloritana dei Pericolanti : Classe di Scienze Fisiche, Matematiche e Naturali, 2004
Our paper contains two main results: (1) the integral manifolds of a distribution together with two Riemann metrics produce potential maps which are in fact least squares approximations of the starting integral manifolds; (2) the least squares energy ...
Udriste, C
doaj   +1 more source

Using physics‐informed neural networks to quantify submarine groundwater discharge under high‐frequency tidal dynamics using heat as a tracer

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Estimating exchange rates of submarine groundwater discharge (SGD) at high temporal resolution over extended periods remains challenging, particularly when using heat as a tracer in highly dynamic environments such as tidal systems. Currently available heat transport models struggle to accurately quantify SGD exchange rates in these settings ...
S. Frei   +3 more
wiley   +1 more source

Unveiling New Perspectives on the Hirota–Maccari System With Multiplicative White Noise

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this study, we delve into the stochastic Hirota–Maccari system, which is subjected to multiplicative noise according to the Itô sense. The stochastic Hirota–Maccari system is significant for its ability to accurately model how stochastic affects nonlinear wave propagation, providing valuable insights into complex systems like fluid dynamics
Mohamed E. M. Alngar   +3 more
wiley   +1 more source

Asymptotic Analysis of the Static Bidomain Model for Pulsed Field Cardiac Ablation

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Cardiac arrhythmias are caused by faulty electrical signals in the heart, which lead to chaotic wave propagation and impaired cardiac function. This work focuses on a non‐thermal ablation technique based on electroporation (EP), a promising method for treating arrhythmias, called pulsed field ablation (PFA).
Annabelle Collin   +2 more
wiley   +1 more source

Interaction of Dirac δ$$ \delta $$‐Waves in the Inviscid Levine and Sleeman Chemotaxis Model

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT This article investigates interactions of δ$$ \delta $$‐shock waves in the inviscid Levine and Sleeman chemotaxis model ut−λ(uv)x=0$$ {u}_t-\lambda {(uv)}_x=0 $$, vt−ux=0$$ {v}_t-{u}_x=0 $$. The analysis employs a distributional product and a solution concept that extends the classical solution concept.
Adelino Paiva
wiley   +1 more source

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