Results 121 to 130 of about 23,176 (145)
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi +6 more
wiley +1 more source
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng +6 more
wiley +1 more source
Proximity Ferroelectricity in Compositionally Graded Structures
We perform the finite element modeling of the polarization switching in the compositionally graded AlN‐Al1‐xScxN and ZnO‐Zn1‐xMgxO structures and reveal the switching of spontaneous polarization in the whole structure in all these systems. The coercive field to switch is significantly lower than the electric breakdown field of the unswitchable AlN and ...
Eugene A. Eliseev +4 more
wiley +1 more source
Advanced Extractables and Leachables Assessment of Microcarriers Used for Adherent Cell Cultures
Graphical Abstract and Lay Summary We present a comprehensive workflow for the Extractables and Leachables (E & L) assessment of microcarriers used in adherent cell culture. Four key components are appied: experimental extractables testing (USP <665>), modelling of extractables release, process modelling, and safety assessment via biocompatibility and ...
Armin Hauk +6 more
wiley +1 more source
PVRI‐GoDeep—A Global Meta‐Registry at the Crossroads of Heart and Lung
PVRI GoDeep is a global meta‐registry that harmonizes high‐quality patient‐level data from pulmonary hypertension registries worldwide. With over 45,000 enrolees already included, it enables robust phenotyping, international comparisons, and clinically relevant research across all PH subgroups beyond the scope of single‐center or national datasets ...
Meike T. Fuenderich +83 more
wiley +1 more source
A comprehensive review of model‐based, data‐driven, and hybrid approaches for Remaining Useful Life (RUL) prediction, emphasizing their role in predictive maintenance, fault diagnosis, and enhancing industrial reliability. ABSTRACT This paper aims to provide a state‐of‐the‐art review of the most recent Remaining Useful Life (RUL) prediction methods ...
Arslan Ahmed Amin +4 more
wiley +1 more source
This study demonstrates that Al2O3–GNP hybrid nanofluids significantly enhance heat transfer in porous rectangular enclosures. Magnetic fields suppress velocity but raise temperature, while higher Biot and Brinkman numbers improve Nusselt number and entropy generation, highlighting effective thermal control in non‐Newtonian HNF systems.
Wajid Ullah +4 more
wiley +1 more source
Abstract As global groundwater levels continue to decline rapidly, there is a growing need for advanced techniques to monitor and manage aquifers effectively. This study focuses on validating a numerical model using seismic data from a small‐scale experimental setup designed to estimate water volume in a porous reservoir.
Mahnaz Khalili +8 more
wiley +1 more source
Abstract String theory has strong implications for cosmology, implying the absence of a cosmological constant, ruling out single‐field slow‐roll inflation, and that black holes decay. The origins of these statements are elucidated within the string‐theoretical swampland programme.
Kay Lehnert
wiley +1 more source

