Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz +10 more
wiley +1 more source
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak +11 more
wiley +1 more source
Extracting wave solutions of coupled system of dual-mode variant boussinesq equation via two analytical methods. [PDF]
Arshed S +5 more
europepmc +1 more source
Effect of HBr on Explosion Limits of Stoichiometric Hydrogen‐oxygen Mixture
ABSTRACT This work, based on numerical simulations, discusses the effect of HBr as an inhibitor on the explosion limit of stoichiometric hydrogen‐oxygen gas mixture in a closed spherical vessel. The numerical simulation solves the complete governing equations for mass, momentum, species and energy.
Chunkan Yu, Peter Glarborg
wiley +1 more source
Exact wave structures and bifurcation for the (2+1)-Dimensional bogoyavlensky-Konopelchenko equation using modified extended direct algebraic technique. [PDF]
Elhady MA +4 more
europepmc +1 more source
Bacillus subtilis Mobilizes Phosphorus by Reshaping P Pools, Sorption, and Enzyme Activities
ABSTRACT Low phosphorus (P) availability constrains crop production in saline‐alkaline soils of Xinjiang, China. We tested whether Bacillus subtilis ( B. subtilis ) mobilizes soil P by altering P fractions, sorption–desorption, and P‐cycling enzymes in a saline‐alkaline cotton soil. Under conventional fertilization, B.
Haiping Xie +5 more
wiley +1 more source
Exact solutions and instability analysis of a fifth-order nonlinear evolution equation exhibiting multi-scale wave structures. [PDF]
Hasan WM +4 more
europepmc +1 more source
Integrating data‐driven weather prediction models and physics‐based NWP models via machine‐learning ensembles significantly enhances short‐term air temperature forecasts over Beijing. The XGBoost‐based ensemble reduces RMSE by over 20% relative to the simple ensemble mean baseline by effectively mitigating systematic bias and diurnal phase shifts ...
Peng He +4 more
wiley +1 more source
Dynamical analysis and exact solitary wave solutions of [Formula: see text]-dimensional integro-differential Jaulent-Miodek equation using two analytical schemes. [PDF]
Nasir B +5 more
europepmc +1 more source
Approximate Reachability for Feedback Linearizable Systems
The backwards reachable set for a dynamical system is the set of states for which there exists a constraint admissible trajectory that reaches a given terminal set. Conventional grid‐based approaches for computing these sets are intractable for many applications.
Vincent Liu +2 more
wiley +1 more source

