Results 91 to 100 of about 270,101 (314)

A numerically reliable approach for the synthesis of periodic FDI filters

open access: yes, 2012
We propose an integrated numerically reliable computational approach to solve fault detection and isolation (FDI) problems for periodic systems. For this purpose, a bank of periodic fault detection filters providing a structured residual set is designed
Varga, Andreas
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Structure from Periodic Motion [PDF]

open access: yes, 2006
We show how to exploit temporal periodicity of moving objects to perform 3D reconstruction. The collection of period-separated frames serve as a surrogate for multiple rigid views of a particular pose of the moving target, thus allowing the use of standard techniques of multiview geometry.
Serge J. Belongie, Josh Wills
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Strongly stable algorithm for computing periodic system zeros

open access: yes, 2003
We propose a computationally efficient and numerically reliable algorithm to compute the finite zeros of a linear discrete-time periodic system. The zeros are defined in terms of the transfer-function matrix corresponding to an equivalent lifted time ...
Varga, Andras
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Bifurcations of periodic orbits and uniform approximations. [PDF]

open access: yes, 1997
We derive uniform approximations for contributions to Gutzwiller's periodic-orbit sum for the spectral density which are valid close to bifurcations of periodic orbits in systems with mixed phase space.
Schomerus, Henning   +3 more
core  

Simplified modelling of the behaviour of 3D-periodic structures such as aircraft heat exchangers [PDF]

open access: yes, 2008
In this paper, experimental, analytical and numerical analysis are used to study and model the mechanical behaviour of a heat exchanger core consisting of a 3D-periodic structure.
Rezaï-Aria, Farhad   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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