Results 141 to 150 of about 128,153 (317)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
The Astronomical JournalCrater II (CraII) is a very intriguing low surface brightness and extended galaxy in the vicinity of our Galaxy. Motivated by its huge area and the number of RR Lyrae stars (RRLSs) detected near to its core, we performed a follow-up campaign to get deep ...
A. Katherina Vivas +7 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Heartbeat Stars Recognition Based on Recurrent Neural Networks: Method and Validation
The Astronomical JournalSince the variety of their light curve morphologies, the vast majority of the known heartbeat stars (HBSs) have been discovered by manual inspection. Machine learning, which has already been successfully applied to the classification of variable stars ...
Min-Yu Li +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Variable X-Ray Emission of the Planet Hosting T Tauri Star CI Tau
The Astronomical JournalWe report results of Chandra X-ray observations of CI Tau, a young magnetically active classical T Tauri star for which previous studies have reported periodic variability attributed to a massive planet in a short-period orbit.
Stephen L. Skinner, Manuel Güdel
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A Plasma Torus around a Young Low-mass Star
The Astrophysical Journal LettersA small fraction of red dwarfs younger than ∼100 million years show structured, periodic optical light curves suggestive of transiting opaque material that corotates with the star. However, the composition, origin, and even the existence of this material
Luke G. Bouma, Moira M. Jardine
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
On the interpretation of new late B- and early A-type periodic variable stars in NGC 3766 [PDF]
, 2013 N. Mowlavï +3 more
openalex +1 more source