Results 61 to 70 of about 3,309 (265)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
On the period of the variable Star V Puppis [PDF]
Astronomische Nachrichten, 1897 n ...
openaire +1 more source
The Astrophysical Journal Supplement SeriesThe LAMOST-Kepler/K2 Medium-Resolution Spectroscopic Survey (LK-MRS) conducted time-domain (TD) medium-resolution spectroscopic observations of 20 LAMOST plates in the Kepler and K2 fields from 2018 to 2023, a phase designated as LK-MRS-I.
Mingfeng Qin +13 more
doaj +1 more source
Multivariate time series transformer embeddings for light curves of periodic variable stars
Astronomy & AstrophysicsContext. Astronomical surveys produce time series data by observing stellar objects across multiple photometry bands. Foundational transformer-based models, such as Astromer, encode each time series as a sequence of embeddings to classify sources ...
Chiong G., Becker I., Protopapas P.
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Rotation Periods of Candidate Single Late-M Dwarfs in TESS
The Astronomical JournalRecent studies suggest that the angular momentum evolution of late-M and brown dwarfs differs from the well-known spin-down evolution of hotter stars. Characterizing the distribution of rotation periods of these objects in the solar neighborhood can help
Samantha Lambier +6 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Young Stellar Objects in the Carina Nebula: Near-infrared Variability and Spectroscopy
The Astronomical JournalWe present a catalog of 652 young stellar objects (YSOs) in the Carina star-forming region. The catalog was constructed by combining near-infrared K _S -band variability from the VISTA Variables in the Vía Láctea eXtended survey and medium-resolution H ...
Jura Borissova +12 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source