Results 91 to 100 of about 123,846 (287)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Magazine sales promotion : a dynamic response analysis [PDF]

open access: yes, 2006
This paper studies the impact and effectiveness of a type of non-price promotion often used in the European periodical magazines industry to stimulate sales, in which a value pack is sold containing the magazine issue plus another product.
Esteban-Bravo, Mercedes   +2 more
core   +1 more source

Special Libraries, December 1975 [PDF]

open access: yes, 1975
Volume 66, Issue 12https://scholarworks.sjsu.edu/sla_sl_1975/1009/thumbnail ...
Special Libraries Association
core   +6 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

The Periodic Table of Evaluation

open access: yesJournal of MultiDisciplinary Evaluation
Evaluation is a vast field of designs and methods in continuous development. The numerous parameters and choices associated with different methodological options can be difficult to fully understand without deep study and desk review. The motivation for the Periodic Table of Evaluation was to create a one-pager visual that catalogues methodological ...
openaire   +2 more sources

Time evolution of continuous-time quantum walks on dynamical percolation graphs

open access: yes, 2013
We study the time evolution of continuous-time quantum walks on randomly changing graphs. At certain moments edges of the graph appear or disappear with a given probability.
Darázs, Zoltán, Kiss, Tamás
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Divulgação de trabalho: considerações sobre os doze anos do caderno de estudos

open access: yesRevista Contabilidade & Finanças, 2002
Este artigo tem o propósito de apresentar uma avaliação do periódico corrente Caderno de Estudos, atual Revista Contabilidade & Finanças - USP, publicado pela Fundação Instituto de Pesquisas Contábeis, Atuariais e Financeiras -FIPECAFI, entidade de apoio
Gilberto de Andrade Martins
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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