Results 91 to 100 of about 5,607,834 (304)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Guidance on Evaluation Inception Reports

open access: yes, 2023
This document provides guidance on how to develop an evaluation Inception Report and its core contents, namely the evaluation purpose, focus, design and ...
CGIAR Independent Evaluation Arrangement
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Report of the IEA Workshop on Evaluating the Quality of Science, Rome, 10-11 December 2015

open access: yes, 2020
IEA organized a 1.5 day (10-11 December 2015) internal workshop to discuss approaches and experiences in assessing science quality, primarily through evaluations in the CGIAR.
CGIAR Independent Evaluation Arrangement
core  

An Evaluation of World Bank Investment Climate Activities

open access: yes, 2004
The Investment Climate Study is a evaluation of the Operations Evaluation Department (OED). The OED report reviews the Bank’s investment climate lending and non-lending activities during fiscal years 1993 through
Operations Evaluation Department
core   +1 more source

Evaluation of the World Bank Group’s Support for Electricity from Renewable Energy Resources, 2000-2017

open access: yes, 2020
The Clean Energy Transition—the pathway for decarbonizing global energy—is essential to foster inclusive and sustainable growth while addressing climate change.
Independent Evaluation Group
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Research on credit counting and risk evaluation for C2C e-commerce

open access: yesTongxin xuebao, 2009
An improved method of credit counting was introduced,which used the interval distribution of commodity prices to rate success trades and used different deducting coefficients to rate failed trades according to different credit rating.A risk evaluation ...
LI Rui-xuan   +3 more
doaj   +2 more sources

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