Results 81 to 90 of about 9,176,045 (364)

Advances in understanding vitamin D deficiency as a risk factor in periodontal disease management

Journal of Mind and Medical Sciences
This study investigates the relationship between periodontal disease and vitamin D deficiency by correlating clinical periodontal parameters with serum levels of vitamin D; (2) Methods: Data from the literature and the periodontal status of two ...
Marina Cristina Giurgiu, George Alexandru Denis Popescu, Stana Paunica, Dragos Nicolae Ciongaru, Brandusa Florina Mocanu, Ana Maria Alexandra Stanescu, Anca Silvia Dumitriu   +6 more
doaj   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase‐1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double‐blind, placebo‐controlled, single‐ and multiple‐ascending dose study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Dipeptidyl peptidase‐1 (DPP‐1) inhibitors have been studied for the treatment of neutrophil‐mediated inflammatory diseases including bronchiectasis, bronchial asthma and cystic fibrosis. This study evaluated the pharmacokinetics, pharmacodynamics, safety and tolerability of DPP‐1 inhibitor HSK31858 in healthy Chinese volunteers.
Yuhao Wang, Chao Yu, Mengyue Hu, Lu Wang, Meixia Chen, Hanmo Liu, Nan Wu, Jie Hou   +7 more
wiley   +1 more source

Awareness and knowledge of periodontal disease among Saudi primary school teachers in Aseer region

Journal of Indian Society of Periodontology, 2017
Background: The consequences of periodontal disease are not limited to the oral cavity. As schools are considered to be one of the principal systems in preventive oral health, teachers' knowledge pertaining to the periodontal disease, their awareness ...
Abdulrahman Ahmed Mohammed Alshehri, Fawaz Dhafer Abdullah Alshehri, Khalid Yahya Abdo Hakami, Zayed Ali Ahmad Assiri, Abdulrahim Abdullah Mohammed Alshehri, Zafer Ali Zafer Alqahtani   +5 more
doaj   +1 more source

Cardiovascular and periodontal diseases

Revista Brasileira de Cirurgia Cardiovascular, 2014
Associate Professor of Cardiac Surgery at the Campinas State University Medical School. E-mail: rkv@uol.com.br Cardiovascular diseases, especially those associated with atherosclerosis, are still one of the main causes of death worldwide. There are well-established risk factors for cardiovascular diseases, one of them being elevated levels of serum ...
openaire   +3 more sources

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Periodontal disease and the metabolic syndrome.

International Dental Journal, 2017
The metabolic syndrome (MetS) is a spectrum of conditions that increase the risk of cardiovascular disease and diabetes mellitus. The components of MetS include dysglycemia, visceral obesity, atherogenic dyslipidemia (elevated triglycerides and low ...

semanticscholar   +1 more source

Expertise‐inspired artificial intelligence pipeline for clinically applicable reconstruction of tooth‐centric radial planes: Development and multicenter validation

BMEMat, EarlyView.
The expertise‐inspired AI pipeline demonstrates significant clinical utility for rapid and precise analysis of dento‐maxillofafcial CBCT and benefits for intelligent oral health management. Abstract Owing to the tooth‐centered nature of most oral diseases, the tooth‐centric radial plane of cone‐beam computed tomography (CBCT) depicts the anatomical and
Zhuohong Gong, Gengbin Cai, Jiayang Zeng, Beichen Wen, Hengyi Liu, Jiahong Lin, Xiaofei Meng, Peisheng Zeng, Jiamin Shi, Rui Xie, Yang Yu, Yin Xiao, Mengru Shi, Ruixuan Wang, Zetao Chen   +14 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source