Results 81 to 90 of about 197,485 (338)

Associations between oral biofilm, periodontal disease, and systemic health: with a focus on atherosclerosis and breast cancer [PDF]

, 2012
The general hypothesis of this series of studies was that oral infections, particularly periodontal disease, by triggering inflammatory reactions detrimentally affect systemic health where inflammations are known to play a role in the pathogenesis ...
Yakob, Maha
core   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source

Influence of the oral status on cardiovascular diseases in an older Italian population [PDF]

, 2018
Oral diseases have been adversely associated with cardiovascular diseases (CVD), which are also the most frequent cause of death in older population. The aim of this study was to investigate the association among oral status indexes and CVD in patients
Basili, Stefania, Dan Trifan, Pompiliu, De Angelis, Francesca, Di Carlo, Stefano, FRATTO, Giovanni, Manzon, Licia   +5 more
core   +1 more source

Decoding Dental Stem Cell Aging: Mechanisms, Therapeutic Strategies, and Beyond

Advanced Science, EarlyView.
Dental stem cell (DSC) aging involves genomic instability, mitochondrial dysfunction, telomere attrition, and epigenetic alterations, leading to impaired proliferation, reduced differentiation potential, and pro‐inflammatory secretory activity. These processes drive cellular senescence and compromise regenerative and immunomodulatory functions, thereby
Xinyuan Zhao, Yunfan Lin, Pei Lin, Ye Lu, Jiarong Zheng, Xu Chen, Zihao Zhou, Li Cui   +7 more
wiley   +1 more source

Antibacterial Effect of Diclofenac Sodium on Enterococcus faecalis.

Frontiers in Dentistry, 2013
Non-steroidal anti-inflammatory drugs (NSAIDs) have shown antibacterial activity in some recent studies. The aim of this study was to evaluate the antibacterial effect of diclofenac against Enterococcus faecalis (E.
Amin Salem-Milani, Esrafil Balaei-Gajan, Saeed Rahimi, Zohreh Moosavi, Ardalan Abdollahi, Parvin Zakeri-Milani, Mehrdad Bolourian   +6 more
doaj  

The dental management of patients at risk of medication-related osteonecrosis of the jaw: New paradigm of primary prevention [PDF]

, 2018
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is a potentially painful and debilitating condition that can considerably affect the quality of life of patients ...
Bedogni, Alberto, Campisi, Giuseppina, Di Fede, Olga, Fusco, Vittorio, Lo Muzio, Lorenzo, Mauceri, Rodolfo, Panzarella, Vera, Sipmo Onj Board, Null   +7 more
core   +2 more sources

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Prevalence of halitosis and evaluation of etiological factors in a Turkish subpopulation [PDF]

, 2016
Aim: The purpose of this study was to estimate the prevalence of halitosis in an adult Turkish subpopulation and to assess the relationship between halitosis and sociodemographics, self reported halitosis, etiological factors, by employing standardized ...
Güngör, Kahraman, Yıldızer Keri̇ş, Eli̇f, Özdede, Meli̇h, Özütürk, Özge   +3 more
core   +2 more sources

FGF9–FGFR2 Signaling via Osteocytes‐Preosteoblasts Crosstalks to Mediate Mechanotransduction‐Driven Intramembranous Osteogenesis in the Underdeveloped Maxilla

Advanced Science, EarlyView.
This study identifies osteocyte‐derived FGF9 as a mechanosensitive factor that impairs osteogenesis in the underdeveloped maxilla by inducing FGFR2 nuclear translocation in preosteoblasts. Mechanical stimulation reduces FGF9 secretion, relieving its inhibitory effect. These findings reveal a novel osteocyte–preosteoblast FGF9–FGFR2 axis in craniofacial
Yiwen Zhou, Lili Chen, Miaomiao Han, Peixiang Zhu, Yanyi Wang, Xuanxuan Yu, Tingyu Reng, Huijuan Wang, Baochao Li, Caixia Zhang, Ziwei Huang, Shuang Lin, Guoyun Wang, Jie Ge, Baosheng Guo, Huang Li   +15 more
wiley   +1 more source

Smart Gated Hollow Mesoporous Silica Hydrogel for Targeting Endoplasmic Reticulum Stress and Promoting Periodontal Tissue Regeneration

Advanced Science, EarlyView.
The hollow mesoporous silica loaded with quercetin (HM‐QU@PEG) is combined with a thermosensitive anti‐bacterial matrix (TF127) to prepare HQUP@TF127. HQUP@TF127 effectively eliminates excessive ROS, alleviates endoplasmic reticulum stress, relieves mitochondrial calcium overload, and blocks the p53‐dependent apoptotic cascade. Furthermore, it enhances
Guichun Wang, Yuxiao Wang, Yang Ding, Xiang Chen, Shuhan Li, Wenqi Zhou, Rui Ma, Maomao Tang, Xinyuan Shao, Zixuan Shu, Ning He, Xiaodong Ma, Jian Guo, Chengjun Peng, Shuangying Gui   +14 more
wiley   +1 more source