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Introduction: this study was conducted to investigate the osteogenic ability of periodontal ligament stem cells (PDLSCs) derived exosomes (PDLSCs-Exos) and the effect of PDLSCs-Exos with hydrogel on alveolar bone defect repairment in the rat.
Yang Zhao+5 more
doaj +2 more sources
Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of the ...
Emmanuel Albuquerque-Souza+10 more
doaj +2 more sources
Healing in Transplanted Teeth with Periodontal Ligament Cultured In Vitro
Regeneration of connective tissue attachment is the ultimate goal of periodontal therapy. It has been suggested that periodontal ligament cells possess the potential to create new connective tissue attachment.
A. Saito+3 more
doaj +2 more sources
Periodontal ligament tissues support neutrophil differentiation and maturation processes [PDF]
IntroductionPeriodontal ligament is the soft connective tissue joining the roots of teeth with alveolar bone. The periodontal ligament presents significant cellular heterogeneity, including fibroblasts, endothelial cells, cementoblasts, osteoblasts ...
Guillermo Villagómez-Olea+5 more
doaj +2 more sources
Effect of different periodontal ligament simulating materials on the incidence of dentinal cracks during root canal preparation [PDF]
Background. The present study was undertaken to evaluate the incidence of dentinal cracks during root canal preparation with different periodontal ligament simulating materials in vitro. Methods. Seventy freshly extracted human mandibular first premolars
Ajita Rathi+5 more
doaj +2 more sources
circRNA CDR1as (CDR1as) has been demonstrated to play important roles in a variety of inflammation-related diseases by acting as miRNA sponges. The present study is aimed at investigating the potential roles of CDR1as in the proliferation of human ...
Fang Wang+4 more
doaj +2 more sources
Stem cells in the periodontal ligament [PDF]
The ability to identify and manipulate stem cells has been a significant advancement in regenerative medicine and has contributed to the development of tissue engineering‐based clinical therapies. Difficulties associated with achieving predictable periodontal regeneration, means that novel techniques such as tissue engineering need to be developed in ...
Sašo Ivanovski+3 more
openalex +5 more sources
Periodontitis is an immune inflammatory disease that leads to progressive destruction of bone and connective tissue, accompanied by the dysfunction and even loss of periodontal ligament stem cells (PDLSCs).
Qin Chen+12 more
semanticscholar +1 more source
Therapeutic potential of periodontal ligament stem cells
Inflammatory periodontal disease known as periodontitis is one of the most common conditions that affect human teeth and often leads to tooth loss. Due to the complexity of the periodontium, which is composed of several tissues, its regeneration and ...
Aline Queiroz+6 more
semanticscholar +1 more source
Periodontium regeneration and repair is a controversial and difficult point in the treatment of periodontosis. The proliferation, differentiation, migration and adhesion of periodontal ligament cells and the dynamic relationship between periodontal ...
LI Qi+3 more
doaj +1 more source