Results 11 to 20 of about 343,225 (186)

Therapeutic potential of periodontal ligament stem cells

open access: yesWorld Journal of Stem Cells, 2021
Inflammatory periodontal disease known as periodontitis is one of the most common conditions that affect human teeth and often leads to tooth loss. Due to the complexity of the periodontium, which is composed of several tissues, its regeneration and ...
Aline Queiroz   +6 more
semanticscholar   +1 more source

Comparative Analysis of Stress in the Periodontal Ligament and Center of Rotation in the Tooth after Orthodontic Treatment Depending on Clear Aligner Thickness—Finite Element Analysis Study

open access: yesMaterials, 2021
Lately, in orthodontic treatments, the use of transparent aligners for the correction of malocclusions has become prominent owing to their intrinsic advantages such as esthetics, comfort, and minimal maintenance.
J. Seo   +9 more
semanticscholar   +1 more source

RETRACTED ARTICLE: Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway

open access: yesStem cell research & therapeutics, 2020
The oral cavity is a complex environment in which periodontal tissue is constantly stimulated by external microorganisms and mechanical forces. Proper mechanical force helps maintain periodontal tissue homeostasis, and improper inflammatory response can ...
Pei-ying Lv   +8 more
semanticscholar   +1 more source

Enhancement of periodontal tissue regeneration by conditioned media from gingiva-derived or periodontal ligament-derived mesenchymal stem cells: a comparative study in rats

open access: yesStem cell research & therapeutics, 2020
Evidence has demonstrated conditioned medium (CM) from periodontal ligament stem cells (PDLSCs) improved periodontal regeneration. Gingival mesenchymal stem cells (GMSCs) have been considered an alternative strategy for regenerative medicine.
Jiling Qiu   +8 more
semanticscholar   +1 more source

Periodontitis-level butyrate-induced ferroptosis in periodontal ligament fibroblasts by activation of ferritinophagy

open access: yesCell Death Discovery, 2020
Loss of periodontal ligament fibroblasts (PDLFs) is one critical issue for regenerating lost periodontal tissues. A wide variety of regulated cell death pathways, such as apoptosis, pyroptosis, and necroptosis have been proposed in the periodontitis ...
Yunhe Zhao   +4 more
semanticscholar   +1 more source

A Computational Model of Force within the Ligaments and Tendons in Progressive Collapsing Foot Deformity [PDF]

open access: yesJournal of Orthopaedic Research, 2022, 2021
Progressive collapsing foot deformity results from degeneration of the ligaments and the posterior tibial tendon (PTT). Our understanding of the relationship between the failures of them remains incomplete. We sought to improve this understanding through computational modeling of force in these soft tissues.
arxiv   +1 more source

Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4

open access: yesCell Proliferation, 2020
Mechanical force plays an important role in modulating stem cell fate and behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus and transfer it into biological signals, and thereby promote alveolar bone ...
S. Jin   +8 more
semanticscholar   +1 more source

Maresin-1 and Resolvin E1 Promote Regenerative Properties of Periodontal Ligament Stem Cells Under Inflammatory Conditions

open access: yesFrontiers in Immunology, 2020
Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of the ...
Emmanuel Albuquerque-Souza   +7 more
semanticscholar   +1 more source

Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis

open access: yesStem Cells, 2020
Loss of tissue attachment as a consequence of bacterial infection and inflammation represents the main therapeutic target for the treatment of periodontitis.
Jing Zhao   +3 more
semanticscholar   +1 more source

Improved methods for detection of β-galactosidase (lacZ) activity in hard tissue [PDF]

open access: yes, 2012
The ß-galactosidase gene (lacZ) of Escherichia coli is widely used as a reporter gene. The expression of lacZ can be detected by enzyme-based histochemical staining using chromogenic substrates such as 5-bromo-4-chloro-3-indolyl-ß-D: -galactoside (X-gal).
A Aguzzi   +27 more
core   +2 more sources

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