Results 11 to 20 of about 343,225 (186)
Therapeutic potential of periodontal ligament stem cells
Inflammatory periodontal disease known as periodontitis is one of the most common conditions that affect human teeth and often leads to tooth loss. Due to the complexity of the periodontium, which is composed of several tissues, its regeneration and ...
Aline Queiroz+6 more
semanticscholar +1 more source
Lately, in orthodontic treatments, the use of transparent aligners for the correction of malocclusions has become prominent owing to their intrinsic advantages such as esthetics, comfort, and minimal maintenance.
J. Seo+9 more
semanticscholar +1 more source
The oral cavity is a complex environment in which periodontal tissue is constantly stimulated by external microorganisms and mechanical forces. Proper mechanical force helps maintain periodontal tissue homeostasis, and improper inflammatory response can ...
Pei-ying Lv+8 more
semanticscholar +1 more source
Evidence has demonstrated conditioned medium (CM) from periodontal ligament stem cells (PDLSCs) improved periodontal regeneration. Gingival mesenchymal stem cells (GMSCs) have been considered an alternative strategy for regenerative medicine.
Jiling Qiu+8 more
semanticscholar +1 more source
Loss of periodontal ligament fibroblasts (PDLFs) is one critical issue for regenerating lost periodontal tissues. A wide variety of regulated cell death pathways, such as apoptosis, pyroptosis, and necroptosis have been proposed in the periodontitis ...
Yunhe Zhao+4 more
semanticscholar +1 more source
A Computational Model of Force within the Ligaments and Tendons in Progressive Collapsing Foot Deformity [PDF]
Progressive collapsing foot deformity results from degeneration of the ligaments and the posterior tibial tendon (PTT). Our understanding of the relationship between the failures of them remains incomplete. We sought to improve this understanding through computational modeling of force in these soft tissues.
arxiv +1 more source
Mechanical force plays an important role in modulating stem cell fate and behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus and transfer it into biological signals, and thereby promote alveolar bone ...
S. Jin+8 more
semanticscholar +1 more source
Maresin-1 (MaR1) and Resolvin E1 (RvE1) are specialized pro-resolving lipid mediators (SPMs) that regulate inflammatory processes. We have previously demonstrated the hard and soft tissue regenerative capacity of RvE1 in an in vivo model of the ...
Emmanuel Albuquerque-Souza+7 more
semanticscholar +1 more source
Loss of tissue attachment as a consequence of bacterial infection and inflammation represents the main therapeutic target for the treatment of periodontitis.
Jing Zhao+3 more
semanticscholar +1 more source
Improved methods for detection of β-galactosidase (lacZ) activity in hard tissue [PDF]
The ß-galactosidase gene (lacZ) of Escherichia coli is widely used as a reporter gene. The expression of lacZ can be detected by enzyme-based histochemical staining using chromogenic substrates such as 5-bromo-4-chloro-3-indolyl-ß-D: -galactoside (X-gal).
A Aguzzi+27 more
core +2 more sources