Emerging Roles of Periodontal Pathogen–Derived Outer Membrane Vesicles in NAFLD [PDF]
International Dental JournalThe rising incidence of nonalcoholic fatty liver disease (NAFLD) poses a great socioeconomic burden worldwide. Also, periodontitis is the most common chronic inflammatory disease caused by a group of oral pathogens, affecting both oral health and ...
Congcong Lv +7 more
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Effects of periodontal pathogen-induced intestinal dysbiosis on transplant immunity in an allogenic skin graft model [PDF]
Scientific Reports, 2023 Periodontal disease can induce dysbiosis, a compositional and functional alteration in the microbiota. Dysbiosis induced by periodontal disease is known to cause systemic inflammation and may affect transplant immunity.
Takanori Mei +8 more
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Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia. [PDF]
J Extracell Vesicles, 2023 Periodontitis is a chronic inflammatory disease caused by periodontal pathogens in subgingival plaque and is associated with systemic inflammatory diseases. Extracellular vesicles (EVs) released from host cells and pathogens carry a variety of biological
Lim Y, Kim HY, Han D, Choi BK.
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More Than Just a Periodontal Pathogen -the Research Progress on Fusobacterium nucleatum. [PDF]
Front Cell Infect Microbiol, 2022 Fusobacterium nucleatum is a common oral opportunistic bacterium that can cause different infections. In recent years, studies have shown that F. nucleatum is enriched in lesions in periodontal diseases, halitosis, dental pulp infection, oral cancer, and
Chen Y +9 more
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The Periodontal Pathogen <i>Fusobacterium nucleatum</i> Exacerbates Alzheimer's Pathogenesis <i>via</i> Specific Pathways. [PDF]
Front Aging Neurosci, 2022 Alzheimer’s Disease (AD) is the most common form of dementia in older adults and has a devastating impact on the patient’s quality of life, which creates a significant socio-economic burden for the affected individuals and their families. In recent years,
Wu H +12 more
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Gemella haemolysans inhibits the growth of the periodontal pathogen Porphyromonas gingivalis. [PDF]
Sci Rep, 2021 The oral microbiome plays an important role in the human microbial community and in maintaining the health of an individual. Imbalances in the oral microbiome may contribute to oral and systemic diseases. The progression of periodontal disease is closely
Miyoshi T +8 more
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Clinical evaluation of periodontal pathogen levels by real-time polymerase chain reaction in peri-implantitis patients. [PDF]
Int J Implant Dent, 2021 The mechanisms underlying the onset and progression of peri-implantitis are similar to those of periodontitis, and the causative bacteria are believed to similar.
Ito T +7 more
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Extracellular vesicles derived from the periodontal pathogen Filifactor alocis induce systemic bone loss through Toll-like receptor 2. [PDF]
J Extracell Vesicles, 2021 Periodontitis is an inflammatory disease induced by local infection in tooth‐supporting tissue. Periodontitis is associated with systemic bone diseases, but little is known about the mechanism of the causal effect of periodontitis on systemic bone ...
Kim HY +4 more
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Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis. [PDF]
Sci Rep, 2020 Results from epidemiological and prospective studies indicate a close association between periodontitis and diabetes. However the mechanisms by which periodontal pathogens influence the development of prediabetes/diabetes are not clear.
Ilievski V +12 more
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Neutrophil mobilization by surface-glycan altered Th17-skewing bacteria mitigates periodontal pathogen persistence and associated alveolar bone loss. [PDF]
PLoS ONE, 2014 Alveolar bone (tooth-supporting bone) erosion is a hallmark of periodontitis, an inflammatory disease that often leads to tooth loss. Periodontitis is caused by a select group of pathogens that form biofilms in subgingival crevices between the gums and ...
Rajendra P Settem +2 more
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