Results 71 to 80 of about 1,561,909 (341)

O uso sistêmico de antibióticos no tratamento da doença periodontal [PDF]

open access: yes, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A boca humana, em condições fisiológias, contém um grande número de bacterias patológicas e não patológicas.
Valente, Ana Clara Luiz
core  

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

open access: yesAdvanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu   +12 more
wiley   +1 more source

The relationship between maternal periodontal disease and preterm low birth weight

open access: yes口腔疾病防治, 2019
Preterm low birth weight newborns are prone to complications during growth and development, such as growth retardation and infectious diseases, and the mortality rate of high-risk infants is higher than that of healthy newborns. Epidemiological data show
XIA Fengjuan, SHEN Xiaoqing
doaj   +1 more source

Diagnostic performance of the periodontal pathogen index (PPI) in discriminating between healthy controls and chronic periodontitis patients.

open access: yes, 2018
Diagnostic performance of the periodontal pathogen index (PPI) in discriminating between healthy controls and chronic periodontitis patients.
Eun-Hye Kim (704148)   +12 more
core   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

open access: yesAdvanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park   +13 more
wiley   +1 more source

Clinical evaluation of salivary periodontal pathogen levels by real-time polymerase chain reaction in patients before dental implant treatment

open access: yesClinical Oral Implants Research, 2014
Objective Periodontal pathogens in dental plaque are the main causative agents of periodontitis and peri-implantitis. Detection of the presence of such periodontal pathogens early would serve as a useful tool in the diagnosis and treatment of this ...
Taichi Ito   +5 more
semanticscholar   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

On putative periodontal pathogens: an epidemiological perspective [PDF]

open access: yesVirulence, 2015
The current understanding on the role of microbiology on periodontitis causation is reviewed. An appraisal of the literature reveals several issues that have limited the attempts to investigate candidate periodontal pathogens as causes of periodontitis and confirms that only limited epidemiological evidence is available.
Lopez, Rodrigo   +2 more
openaire   +2 more sources

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

Hyperlipidemia Impaired Innate Immune Response to Periodontal Pathogen Porphyromonas gingivalis in Apolipoprotein E Knockout Mice

open access: yesPLoS ONE, 2013
A finely-tuned innate immune response plays a pivotal role in protecting host against bacterial invasion during periodontal disease progression. Hyperlipidemia has been suggested to exacerbate periodontal health condition.
L. Lei   +3 more
semanticscholar   +1 more source

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