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Human Umbilical Cord Mesenchymal Stem Cells: Current Literature and Role in Periodontal Regeneration

open access: yesCells, 2022
Periodontal disease can cause irreversible damage to tooth-supporting tissues such as the root cementum, periodontal ligament, and alveolar bone, eventually leading to tooth loss.
Muhammad Saad Shaikh   +5 more
doaj   +1 more source

Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review [PDF]

open access: yes, 2015
Intrabony periodontal defects are a frequent complication of periodontitis and, if left untreated, may negatively affect long-term tooth prognosis. The optimal outcome of treatment in intrabony defects is considered to be the absence of bleeding on ...
Ivanovic, Aleksandar   +7 more
core   +1 more source

Immunomodulatory Microneedle Patch for Periodontal Tissue Regeneration [PDF]

open access: yes, 2021
Periodontal diseases are caused by microbial infection and the recruitment of destructive immune cells. Current therapies mainly deal with bacteria elimination, but the regeneration of periodontal tissues remains a challenge.
Butte, Manish J.   +20 more
core   +1 more source

NexGen regen? Challenges and opportunities for growth factors and signaling agents in periodontal regeneration at intrabony defects

open access: yesFrontiers in Dental Medicine, 2023
Regeneration of periodontal tissues that have been destroyed by inflammatory periodontitis involves the initiation of tissue engineering and wound healing of multiple tissues involved in the function of the teeth, including the periodontal ligament ...
Maria L. Geisinger
doaj   +1 more source

Stem cell applications in periodontal regeneration

open access: yes, 2022
Introduction: What Is Periodontal Regeneration? Periodontal regeneration is the full restoration of a damaged periodontal attachment apparatus (cementum, periodontal ligament, and alveolar bone) to its original architecture and function.1 It is a ...
Ivanovski, S.   +3 more
core   +1 more source

Enhancing proliferation and optimizing the culture condition for human bone marrow stromal cells using hypoxia and fibroblast growth factor-2

open access: yesStem Cell Research, 2018
This study aimed to determine the cellular characteristics and behaviors of human bone marrow stromal cells (hBMSCs) expanded in media in a hypoxic or normoxic condition and with or without fibroblast growth factor-2 (FGF-2) treatment.
Jung-Seok Lee   +5 more
doaj   +1 more source

Lithium-calcium-silicate bioceramics stimulating cementogenic/osteogenic differentiation of periodontal ligament cells and periodontal regeneration

open access: yes, 2019
The ultimate goal of treatment of periodontal disease is not only to control inflammation and further to prevent development of the lesion, but also to achieve regeneration of the destroyed periodontal tissue.
Zhatig, Qian   +7 more
core   +1 more source

Autogenous Mesenchymal Stem Cells from the Vertebral Body Enhance Intervertebral Disc Regeneration via Paracrine Interaction: An in Vitro Pilot Study

open access: yesCell Transplantation, 2016
Several in vivo studies have found that transplanting mesenchymal stem cells (MSCs) into degenerative intervertebral discs (IVDs) leads to regeneration of disc cells.
Eun-Kyung Shim   +6 more
doaj   +1 more source

In Vitro and In Vivo Anti-Inflammatory Effects of TEES-10®, a Mixture of Ethanol Extracts of Ligularia stenocephala Matsum. & Koidz. and Secale cereale L. Sprout, on Gingivitis and Periodontitis

open access: yesDentistry Journal, 2022
Gingivitis and periodontitis are inflammatory disorders caused by dental plaque and calculus. These disorders often lead to tooth loss if not treated properly.
Seungah Lee   +10 more
doaj   +1 more source

Cell Secretome from Mesenchymal Stem Cells for Periodontal Regeneration [PDF]

open access: yes
Periodontitis affects approximately 50% of the global adult population and results in varying degrees of periodontal destruction. The regeneration of periodontal tissue is in great demand but is currently difficult to achieve.
Zhang, Xiaoxin   +5 more
core   +1 more source

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