Results 51 to 60 of about 31,579 (302)

Enhanced adipogenic differentiation and reduced collagen synthesis induced by human periodontal ligament stem cells might underlie the negative effect of recombinant human bone morphogenetic protein-2 on periodontal regeneration.

, 2011
BACKGROUND AND OBJECTIVE: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a potent inducer for the regeneration of mineralized tissue, but has a limited effect on the regeneration of cementum and periodontal ligament (PDL).
김창성, 조규성, 정임희, 최성호, 박정철, 김종관   +5 more
core   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Comparative Analysis of Bone Regeneration According to Particle Type and Barrier Membrane for Octacalcium Phosphate Grafted into Rabbit Calvarial Defects

Bioengineering
This animal study was aimed to evaluate the efficacy of new bone formation and volume maintenance according to the particle type and the collagen membrane function for grafted octacalcium phosphate (OCP) in rabbit calvarial defects.
Se-Wook Pyo, Jeong-Won Paik, Da-Na Lee, Young-Wook Seo, Jin-Young Park, Sunjai Kim, Seong-Ho Choi   +6 more
doaj   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Recent advances in periodontal regeneration: A biomaterial perspective

Bioactive Materials, 2020
Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting approximately 47% of adults aged 30 years or older in the United States.
Yongxi Liang, Xianghong Luan, Xiaohua Liu   +2 more
doaj   +1 more source

Dental and Periodontal Tissues Formation and Regeneration: Current Approaches and Future Challenges

, 2016
Sequential and reciprocal interactions between oral epithelial and cranial neural crest-derived mesenchymal cells give rise to the teeth and periodontium. Teeth are vital organs containing a rich number of blood vessels and nerve fibers within the dental
Thimios Mitsiadis, Arana Chavez, Victor E., Mitsiadis, Thimios, Giovanna Orsini, Orsini, Giovanna, Victor E. Arana-Chavez   +5 more
core   +1 more source

3D Bioprinting of a Bioactive Composite Scaffold for Cell Delivery in Periodontal Tissue Regeneration

, 2023
Hydrogels have been widely applied to the fabrication of tissue engineering scaffolds via three-dimensional (3D) bioprinting because of their extracellular matrix-like properties, capacity for living cell encapsulation, and shapeable customization ...
Pan, Yuqian, Pan, Y, Ma, Chaoyang, Hongling Zhao, Liang, L, Zhao, Hongling, Yuqian Pan, Liang, Liyu, Guohou Miao, Xiao, Y, Li, Wenzhi, Miao, G, Zhang, Q, Yang, Xuechao, Xiao, Yin, Zhao, H, Qing Zhang, Yang, X, Miao, Guohou, Xuechao Yang, Ma, C, Chaoyang Ma, Liyu Liang, Yin Xiao, Li, W, Wenzhi Li, Zhang, Qing   +26 more
core   +1 more source

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source

Influência do extrato hidroalcoólico de Polygala Paniculata como coadjuvante no tratamento da doença periodontal induzida em ratos [PDF]

, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A doença periodontal é uma doença inflamatória, caracterizada por uma infecção bacteriana crônica presente nas estruturas de suporte dos dentes e que se ...
Souza, Camila Rodrigues de
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