Results 71 to 80 of about 497,127 (300)

Which biomaterials may promote periodontal regeneration in intrabony periodontal defects? A systematic review of preclinical studies.

, 2014
OBJECTIVE To systematically analyze the regenerative effect of the available biomaterials either alone or in various combinations for the treatment of periodontal intrabony defects as evaluated in preclinical histologic studies.
Ivanovic, Aleksandar, Miron, Richard, Sculean, Anton, Nikou, George, Nikolidakis, Dimitris   +4 more
core   +1 more source

Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review [PDF]

, 2015
Intrabony periodontal defects are a frequent complication of periodontitis and, if left untreated, may negatively affect long-term tooth prognosis. The optimal outcome of treatment in intrabony defects is considered to be the absence of bleeding on ...
Ivanovic, Aleksandar, Stavropoulos, Andreas, L.C. Chapple, Ian, Stavropoulos, Andreas,, Chapple, Iain L C, Sculean, Anton, Nikou, George, Nikolidakis, Dimitris   +7 more
core   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

In vitro biomimetic development of artificial dental calculus: a proof of concept study

BMC Oral Health
Background To develop an in vitro model to generate dental calculus through a standardized process of biofilm mineralization, and compare it with natural human dental calculus .
Jae-Kook Cha, Kyeong-Won Paeng, Seung Ha Yoo, Chae Hyun Lee, Yoon-Hee Kwon, Ui-Won Jung, Baek-Il Kim, Hoi-In Jung, Magda Feres, Mariano Sanz   +9 more
doaj   +1 more source

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration

Stem Cell Research & Therapy, 2019
Background The inflammation and regeneration process may be accompanied by the shift in the M1/M2 polarization of macrophages to adapt to extracellular signals.
Jiaying Liu, Bin Chen, Jun Bao, Yangheng Zhang, Lang Lei, Fuhua Yan   +5 more
doaj   +1 more source

Mesenchymal stem cell-based tissue regeneration therapies for periodontitis

Regenerative Therapy, 2020
Periodontitis is commonly observed and is an important concern in dental health. It is characterized by a multifactorial etiology, including imbalance of oral microbiota, mechanical stress, and systemic diseases such as diabetes mellitus.
Takehito Ouchi, Taneaki Nakagawa
doaj   +1 more source

Guided tissue regeneration may modulate gene expression in periodontal intrabony defects: a human study

, 2015
Background and Objective: Guided tissue regeneration has been shown to lead to periodontal regeneration; however, the mechanisms involved remain to be clarified.
Goncalves, PF, Lima, LL, Casati, MZ, Sallum, EA, Nociti, FH   +4 more
core   +1 more source

Bifunctional injectable selenium‐containing polyurethane hydrogels for periodontal regeneration through endoplasmic reticulum stress modulation

BMEMat, EarlyView.
Graphical illustration of the synthesis, biological functions and mechanisms of bifunctional injectable selenium‐containing polyurethane hydrogels. Abstract Periodontitis causes progressive destruction of both periodontal soft and hard tissues, leading to tooth loss and functional impairment.
Mingchu Zhao, Mo Zhai, Zhuoxin Ge, Xiaodong Guo, Zhuqing Wan, Xiaoqiang Bai, Huaping Xu, Yongsheng Zhou, Longwei Lv   +8 more
wiley   +1 more source